Chipuk JE - Search Results

1

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins.

Beverly LJ, Howell LA, Hernandez-Corbacho M, Casson L, Chipuk JE, Siskind LJ. Beverly LJ, et al. Among authors: chipuk je. Biochem J. 2013 May 15;452(1):111-9. doi: 10.1042/BJ20130147. Biochem J. 2013. PMID: 23480852 Free PMC article.

2

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.

Chipuk JE, McStay GP, Bharti A, Kuwana T, Clarke CJ, Siskind LJ, Obeid LM, Green DR. Chipuk JE, et al. Cell. 2012 Mar 2;148(5):988-1000. doi: 10.1016/j.cell.2012.01.038. Cell. 2012. PMID: 22385963 Free PMC article.

3

Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis.

Renault TT, Chipuk JE. Renault TT, et al. Among authors: chipuk je. Chem Biol. 2014 Jan 16;21(1):114-23. doi: 10.1016/j.chembiol.2013.10.009. Epub 2013 Nov 21. Chem Biol. 2014. PMID: 24269152 Free PMC article. Review.

4

Physiological and Pharmacological Control of BAK, BAX, and Beyond.

Luna-Vargas MPA, Chipuk JE. Luna-Vargas MPA, et al. Among authors: chipuk je. Trends Cell Biol. 2016 Dec;26(12):906-917. doi: 10.1016/j.tcb.2016.07.002. Epub 2016 Aug 4. Trends Cell Biol. 2016. PMID: 27498846 Free PMC article. Review.

5

MDM2 and mitochondrial function: One complex intersection.

Rubio-Patiño C, Trotta AP, Chipuk JE. Rubio-Patiño C, et al. Among authors: chipuk je. Biochem Pharmacol. 2019 Apr;162:14-20. doi: 10.1016/j.bcp.2018.10.032. Epub 2018 Nov 1. Biochem Pharmacol. 2019. PMID: 30391206 Free PMC article. Review.

6

BAK/BAX activation and cytochrome c release assays using isolated mitochondria.

Renault TT, Floros KV, Chipuk JE. Renault TT, et al. Among authors: chipuk je. Methods. 2013 Jun 1;61(2):146-55. doi: 10.1016/j.ymeth.2013.03.030. Epub 2013 Apr 6. Methods. 2013. PMID: 23567751 Free PMC article.

7

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.

Serasinghe MN, Missert DJ, Asciolla JJ, Podgrabinska S, Wieder SY, Izadmehr S, Belbin G, Skobe M, Chipuk JE. Serasinghe MN, et al. Among authors: chipuk je. Oncogene. 2015 Feb 12;34(7):857-67. doi: 10.1038/onc.2014.21. Epub 2014 Mar 10. Oncogene. 2015. PMID: 24608435 Free PMC article.

8

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.

Renault TT, Elkholi R, Bharti A, Chipuk JE. Renault TT, et al. Among authors: chipuk je. J Biol Chem. 2014 Sep 19;289(38):26481-26491. doi: 10.1074/jbc.M114.569632. Epub 2014 Aug 5. J Biol Chem. 2014. PMID: 25096574 Free PMC article.

9

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.

Chipuk JE, Fisher JC, Dillon CP, Kriwacki RW, Kuwana T, Green DR. Chipuk JE, et al. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20327-32. doi: 10.1073/pnas.0808036105. Epub 2008 Dec 12. Proc Natl Acad Sci U S A. 2008. PMID: 19074266 Free PMC article.

10

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.

Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, Nunnari J. Cassidy-Stone A, et al. Among authors: chipuk je. Dev Cell. 2008 Feb;14(2):193-204. doi: 10.1016/j.devcel.2007.11.019. Dev Cell. 2008. PMID: 18267088 Free PMC article.

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