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PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.
Rouschop KM, Dubois LJ, Keulers TG, van den Beucken T, Lambin P, Bussink J, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: koritzinsky m. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4622-7. doi: 10.1073/pnas.1210633110. Epub 2013 Mar 7. Proc Natl Acad Sci U S A. 2013. PMID: 23471998 Free PMC article.
Dabrafenib Alters MDSC Differentiation and Function by Activation of GCN2.
Ciudad MT, Quevedo R, Lamorte S, Jin R, Nzirorera N, Koritzinsky M, McGaha TL. Ciudad MT, et al. Among authors: koritzinsky m. Cancer Res Commun. 2024 Mar 13;4(3):765-784. doi: 10.1158/2767-9764.CRC-23-0376. Cancer Res Commun. 2024. PMID: 38421883 Free PMC article.
Hypoxia as a target for combined modality treatments.
Wouters BG, Weppler SA, Koritzinsky M, Landuyt W, Nuyts S, Theys J, Chiu RK, Lambin P. Wouters BG, et al. Among authors: koritzinsky m. Eur J Cancer. 2002 Jan;38(2):240-57. doi: 10.1016/s0959-8049(01)00361-6. Eur J Cancer. 2002. PMID: 11803141 Review.
Modulation of cell death in the tumor microenvironment.
Wouters BG, Koritzinsky M, Chiu RK, Theys J, Buijsen J, Lambin P. Wouters BG, et al. Among authors: koritzinsky m. Semin Radiat Oncol. 2003 Jan;13(1):31-41. doi: 10.1053/srao.2003.50004. Semin Radiat Oncol. 2003. PMID: 12520462 Review.
Control of the hypoxic response through regulation of mRNA translation.
Wouters BG, van den Beucken T, Magagnin MG, Koritzinsky M, Fels D, Koumenis C. Wouters BG, et al. Among authors: koritzinsky m. Semin Cell Dev Biol. 2005 Aug-Oct;16(4-5):487-501. doi: 10.1016/j.semcdb.2005.03.009. Semin Cell Dev Biol. 2005. PMID: 15896987 Review.
78 results