Chen-Izu Y - Search Results

1

The force-frequency relationship: insights from mathematical modeling.

Puglisi JL, Negroni JA, Chen-Izu Y, Bers DM. Puglisi JL, et al. Adv Physiol Educ. 2013 Mar;37(1):28-34. doi: 10.1152/advan.00072.2011. Adv Physiol Educ. 2013. PMID: 23471245 Free PMC article. Review.

2

Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling.

Jian Z, Han H, Zhang T, Puglisi J, Izu LT, Shaw JA, Onofiok E, Erickson JR, Chen YJ, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff JC, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu Y. Jian Z, et al. Sci Signal. 2014 Mar 18;7(317):ra27. doi: 10.1126/scisignal.2005046. Sci Signal. 2014. PMID: 24643800 Free PMC article.

3

FRET-based trilateration of probes bound within functional ryanodine receptors.

Svensson B, Oda T, Nitu FR, Yang Y, Cornea I, Chen-Izu Y, Fessenden JD, Bers DM, Thomas DD, Cornea RL. Svensson B, et al. Biophys J. 2014 Nov 4;107(9):2037-48. doi: 10.1016/j.bpj.2014.09.029. Biophys J. 2014. PMID: 25418089 Free PMC article.

4

A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current.

Yang PC, Song Y, Giles WR, Horvath B, Chen-Izu Y, Belardinelli L, Rajamani S, Clancy CE. Yang PC, et al. J Physiol. 2015 Mar 15;593(6):1429-42. doi: 10.1113/jphysiol.2014.279554. J Physiol. 2015. PMID: 25545172 Free PMC article.

5

Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia.

Bers DM, Chen-Izu Y. Bers DM, et al. J Physiol. 2015 Mar 15;593(6):1327-9. doi: 10.1113/JP270133. J Physiol. 2015. PMID: 25772288 Free PMC article. No abstract available.

6

Deranged sodium to sudden death.

Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, Qu Z, Rajamani S, Rippinger CM, Sejersted OM, O'Rourke B, Weiss JN, Varró A, Zaza A. Clancy CE, et al. J Physiol. 2015 Mar 15;593(6):1331-45. doi: 10.1113/jphysiol.2014.281204. J Physiol. 2015. PMID: 25772289 Free PMC article. Review.

7

Na+ channel function, regulation, structure, trafficking and sequestration.

Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM. Chen-Izu Y, et al. J Physiol. 2015 Mar 15;593(6):1347-60. doi: 10.1113/jphysiol.2014.281428. J Physiol. 2015. PMID: 25772290 Free PMC article. Review.

8

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart.

Shattock MJ, Ottolia M, Bers DM, Blaustein MP, Boguslavskyi A, Bossuyt J, Bridge JH, Chen-Izu Y, Clancy CE, Edwards A, Goldhaber J, Kaplan J, Lingrel JB, Pavlovic D, Philipson K, Sipido KR, Xie ZJ. Shattock MJ, et al. J Physiol. 2015 Mar 15;593(6):1361-82. doi: 10.1113/jphysiol.2014.282319. J Physiol. 2015. PMID: 25772291 Free PMC article. Review.

9

Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.

Oda T, Yang Y, Uchinoumi H, Thomas DD, Chen-Izu Y, Kato T, Yamamoto T, Yano M, Cornea RL, Bers DM. Oda T, et al. J Mol Cell Cardiol. 2015 Aug;85:240-8. doi: 10.1016/j.yjmcc.2015.06.009. Epub 2015 Jun 16. J Mol Cell Cardiol. 2015. PMID: 26092277 Free PMC article.

10

CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.

Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM. Uchinoumi H, et al. J Mol Cell Cardiol. 2016 Sep;98:62-72. doi: 10.1016/j.yjmcc.2016.06.007. Epub 2016 Jun 16. J Mol Cell Cardiol. 2016. PMID: 27318036 Free PMC article.

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