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TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator.
Tsai VW, Macia L, Johnen H, Kuffner T, Manadhar R, Jørgensen SB, Lee-Ng KK, Zhang HP, Wu L, Marquis CP, Jiang L, Husaini Y, Lin S, Herzog H, Brown DA, Sainsbury A, Breit SN. Tsai VW, et al. Among authors: wu l. PLoS One. 2013;8(2):e55174. doi: 10.1371/journal.pone.0055174. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23468844 Free PMC article.
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.
Johnen H, Lin S, Kuffner T, Brown DA, Tsai VW, Bauskin AR, Wu L, Pankhurst G, Jiang L, Junankar S, Hunter M, Fairlie WD, Lee NJ, Enriquez RF, Baldock PA, Corey E, Apple FS, Murakami MM, Lin EJ, Wang C, During MJ, Sainsbury A, Herzog H, Breit SN. Johnen H, et al. Among authors: wu l. Nat Med. 2007 Nov;13(11):1333-40. doi: 10.1038/nm1677. Epub 2007 Nov 4. Nat Med. 2007. PMID: 17982462
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease.
Breit SN, Carrero JJ, Tsai VW, Yagoutifam N, Luo W, Kuffner T, Bauskin AR, Wu L, Jiang L, Barany P, Heimburger O, Murikami MA, Apple FS, Marquis CP, Macia L, Lin S, Sainsbury A, Herzog H, Law M, Stenvinkel P, Brown DA. Breit SN, et al. Among authors: wu l. Nephrol Dial Transplant. 2012 Jan;27(1):70-5. doi: 10.1093/ndt/gfr575. Epub 2011 Sep 22. Nephrol Dial Transplant. 2012. PMID: 21940482
Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality.
Wiklund FE, Bennet AM, Magnusson PK, Eriksson UK, Lindmark F, Wu L, Yaghoutyfam N, Marquis CP, Stattin P, Pedersen NL, Adami HO, Grönberg H, Breit SN, Brown DA. Wiklund FE, et al. Among authors: wu l. Aging Cell. 2010 Dec;9(6):1057-64. doi: 10.1111/j.1474-9726.2010.00629.x. Epub 2010 Oct 21. Aging Cell. 2010. PMID: 20854422 Free PMC article.
Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model.
Lu S, Yin Z, Wu L, Sun Y, Chen J, Wu LMN, Oblinger JL, Blake DC, Landegger LD, Seist R, Ho W, Xiu B, Jones AP, Muzikansky A, Stankovic KM, Plotkin SR, Chang LS, Xu L. Lu S, et al. Among authors: wu lmn, wu l. bioRxiv [Preprint]. 2024 Dec 29:2024.12.29.630658. doi: 10.1101/2024.12.29.630658. bioRxiv. 2024. PMID: 39763968 Free PMC article. Preprint.
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