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PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.
Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS. Mikelis CM, et al. Among authors: fukuhara s. J Biol Chem. 2013 Apr 26;288(17):12232-43. doi: 10.1074/jbc.M112.428599. Epub 2013 Mar 6. J Biol Chem. 2013. PMID: 23467409 Free PMC article.
RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.
Mikelis CM, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams RH, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS. Mikelis CM, et al. Among authors: fukuhara s. Nat Commun. 2015 Apr 10;6:6725. doi: 10.1038/ncomms7725. Nat Commun. 2015. PMID: 25857352 Free PMC article.
SPECs, small binding proteins for Cdc42.
Pirone DM, Fukuhara S, Gutkind JS, Burbelo PD. Pirone DM, et al. Among authors: fukuhara s. J Biol Chem. 2000 Jul 28;275(30):22650-6. doi: 10.1074/jbc.M002832200. J Biol Chem. 2000. PMID: 10816584 Free article.
1,443 results