Ho MC - Search Results

1

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.

Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D. Ho MC, et al. PLoS One. 2013;8(2):e57008. doi: 10.1371/journal.pone.0057008. Epub 2013 Feb 25. PLoS One. 2013. PMID: 23451136 Free PMC article.

2

Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.

Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL. Gutierrez JA, et al. Among authors: ho mc. Nat Chem Biol. 2009 Apr;5(4):251-7. doi: 10.1038/nchembio.153. Epub 2009 Mar 8. Nat Chem Biol. 2009. PMID: 19270684 Free PMC article.

3

A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.

Burgos ES, Ho MC, Almo SC, Schramm VL. Burgos ES, et al. Among authors: ho mc. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13748-53. doi: 10.1073/pnas.0903898106. Epub 2009 Aug 4. Proc Natl Acad Sci U S A. 2009. PMID: 19666527 Free PMC article.

4

Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.

Ho MC, Cassera MB, Madrid DC, Ting LM, Tyler PC, Kim K, Almo SC, Schramm VL. Ho MC, et al. Biochemistry. 2009 Oct 13;48(40):9618-26. doi: 10.1021/bi9012484. Biochemistry. 2009. PMID: 19728741 Free PMC article.

5

Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins.

Ho MC, Sturm MB, Almo SC, Schramm VL. Ho MC, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20276-81. doi: 10.1073/pnas.0911606106. Epub 2009 Nov 17. Proc Natl Acad Sci U S A. 2009. PMID: 19920175 Free PMC article.

6

Four generations of transition-state analogues for human purine nucleoside phosphorylase.

Ho MC, Shi W, Rinaldo-Matthis A, Tyler PC, Evans GB, Clinch K, Almo SC, Schramm VL. Ho MC, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4805-12. doi: 10.1073/pnas.0913439107. Epub 2010 Mar 8. Proc Natl Acad Sci U S A. 2010. PMID: 20212140 Free PMC article.

7

Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.

Guan R, Ho MC, Almo SC, Schramm VL. Guan R, et al. Among authors: ho mc. Biochemistry. 2011 Feb 22;50(7):1247-54. doi: 10.1021/bi101642d. Epub 2011 Jan 25. Biochemistry. 2011. PMID: 21197954 Free PMC article.

8

A high-affinity adenosine kinase from Anopheles gambiae.

Cassera MB, Ho MC, Merino EF, Burgos ES, Rinaldo-Matthis A, Almo SC, Schramm VL. Cassera MB, et al. Among authors: ho mc. Biochemistry. 2011 Mar 22;50(11):1885-93. doi: 10.1021/bi101921w. Epub 2011 Feb 15. Biochemistry. 2011. PMID: 21247194 Free PMC article.

9

Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.

Guan R, Ho MC, Brenowitz M, Tyler PC, Evans GB, Almo SC, Schramm VL. Guan R, et al. Among authors: ho mc. Biochemistry. 2011 Nov 29;50(47):10408-17. doi: 10.1021/bi201321x. Epub 2011 Nov 7. Biochemistry. 2011. PMID: 21985704 Free PMC article.

10

Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

Cassera MB, Hazleton KZ, Merino EF, Obaldia N 3rd, Ho MC, Murkin AS, DePinto R, Gutierrez JA, Almo SC, Evans GB, Babu YS, Schramm VL. Cassera MB, et al. Among authors: ho mc. PLoS One. 2011;6(11):e26916. doi: 10.1371/journal.pone.0026916. Epub 2011 Nov 11. PLoS One. 2011. PMID: 22096507 Free PMC article.

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