Nussinov R - Search Results

1

Alzheimer's disease: which type of amyloid-preventing drug agents to employ?

Jang H, Connelly L, Arce FT, Ramachandran S, Lal R, Kagan BL, Nussinov R. Jang H, et al. Among authors: nussinov r. Phys Chem Chem Phys. 2013 Jun 21;15(23):8868-77. doi: 10.1039/c3cp00017f. Epub 2013 Feb 28. Phys Chem Chem Phys. 2013. PMID: 23450150 Free PMC article. Review.

2

Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects.

Ma B, Nussinov R. Ma B, et al. Among authors: nussinov r. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14126-31. doi: 10.1073/pnas.212206899. Epub 2002 Oct 21. Proc Natl Acad Sci U S A. 2002. PMID: 12391326 Free PMC article.

3

Interaction of protegrin-1 with lipid bilayers: membrane thinning effect.

Jang H, Ma B, Woolf TB, Nussinov R. Jang H, et al. Among authors: nussinov r. Biophys J. 2006 Oct 15;91(8):2848-59. doi: 10.1529/biophysj.106.084046. Epub 2006 Jul 21. Biophys J. 2006. PMID: 16861271 Free PMC article.

4

Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect.

Jang H, Ma B, Nussinov R. Jang H, et al. Among authors: nussinov r. BMC Struct Biol. 2007 Apr 2;7:21. doi: 10.1186/1472-6807-7-21. BMC Struct Biol. 2007. PMID: 17407565 Free PMC article.

5

Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.

Jang H, Zheng J, Nussinov R. Jang H, et al. Among authors: nussinov r. Biophys J. 2007 Sep 15;93(6):1938-49. doi: 10.1529/biophysj.107.110148. Epub 2007 May 25. Biophys J. 2007. PMID: 17526580 Free PMC article.

6

Modeling the Alzheimer Abeta17-42 fibril architecture: tight intermolecular sheet-sheet association and intramolecular hydrated cavities.

Zheng J, Jang H, Ma B, Tsai CJ, Nussinov R. Zheng J, et al. Among authors: nussinov r. Biophys J. 2007 Nov 1;93(9):3046-57. doi: 10.1529/biophysj.107.110700. Epub 2007 Aug 3. Biophys J. 2007. PMID: 17675353 Free PMC article.

7

New structures help the modeling of toxic amyloidbeta ion channels.

Jang H, Zheng J, Lal R, Nussinov R. Jang H, et al. Among authors: nussinov r. Trends Biochem Sci. 2008 Feb;33(2):91-100. doi: 10.1016/j.tibs.2007.10.007. Epub 2008 Jan 7. Trends Biochem Sci. 2008. PMID: 18182298 Review.

8

Beta2-microglobulin amyloid fragment organization and morphology and its comparison to Abeta suggests that amyloid aggregation pathways are sequence specific.

Zheng J, Jang H, Nussinov R. Zheng J, et al. Among authors: nussinov r. Biochemistry. 2008 Feb 26;47(8):2497-509. doi: 10.1021/bi7019194. Epub 2008 Jan 24. Biochemistry. 2008. PMID: 18215070

9

Annular structures as intermediates in fibril formation of Alzheimer Abeta17-42.

Zheng J, Jang H, Ma B, Nussinov R. Zheng J, et al. Among authors: nussinov r. J Phys Chem B. 2008 Jun 5;112(22):6856-65. doi: 10.1021/jp711335b. Epub 2008 May 6. J Phys Chem B. 2008. PMID: 18457440 Free PMC article.

10

Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels.

Jang H, Ma B, Lal R, Nussinov R. Jang H, et al. Among authors: nussinov r. Biophys J. 2008 Nov 15;95(10):4631-42. doi: 10.1529/biophysj.108.134551. Epub 2008 Aug 15. Biophys J. 2008. PMID: 18708452 Free PMC article.

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