Motoi Y - Search Results

1

Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing.

Kanno A, Yamamoto C, Onji M, Fukui R, Saitoh S, Motoi Y, Shibata T, Matsumoto F, Muta T, Miyake K. Kanno A, et al. Among authors: motoi y. Int Immunol. 2013 Jul;25(7):413-22. doi: 10.1093/intimm/dxt007. Epub 2013 Feb 26. Int Immunol. 2013. PMID: 23446849

2

Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes.

Shibata T, Motoi Y, Tanimura N, Yamakawa N, Akashi-Takamura S, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2011 Aug;23(8):503-10. doi: 10.1093/intimm/dxr044. Epub 2011 Jun 28. Int Immunol. 2011. PMID: 21712422

3

PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells.

Shibata T, Takemura N, Motoi Y, Goto Y, Karuppuchamy T, Izawa K, Li X, Akashi-Takamura S, Tanimura N, Kunisawa J, Kiyono H, Akira S, Kitamura T, Kitaura J, Uematsu S, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2012 Oct;24(10):613-23. doi: 10.1093/intimm/dxs068. Epub 2012 Jul 25. Int Immunol. 2012. PMID: 22836022

4

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

Onji M, Kanno A, Saitoh S, Fukui R, Motoi Y, Shibata T, Matsumoto F, Lamichhane A, Sato S, Kiyono H, Yamamoto K, Miyake K. Onji M, et al. Among authors: motoi y. Nat Commun. 2013;4:1949. doi: 10.1038/ncomms2949. Nat Commun. 2013. PMID: 23752491 Free article.

5

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

Motoi Y, Shibata T, Takahashi K, Kanno A, Murakami Y, Li X, Kasahara T, Miyake K. Motoi Y, et al. Int Immunol. 2014 Oct;26(10):563-73. doi: 10.1093/intimm/dxu054. Epub 2014 May 24. Int Immunol. 2014. PMID: 24860120

6

Roles of the cleaved N-terminal TLR3 fragment and cell surface TLR3 in double-stranded RNA sensing.

Murakami Y, Fukui R, Motoi Y, Kanno A, Shibata T, Tanimura N, Saitoh S, Miyake K. Murakami Y, et al. Among authors: motoi y. J Immunol. 2014 Nov 15;193(10):5208-17. doi: 10.4049/jimmunol.1400386. Epub 2014 Oct 10. J Immunol. 2014. PMID: 25305318

7

Guanosine and its modified derivatives are endogenous ligands for TLR7.

Shibata T, Ohto U, Nomura S, Kibata K, Motoi Y, Zhang Y, Murakami Y, Fukui R, Ishimoto T, Sano S, Ito T, Shimizu T, Miyake K. Shibata T, et al. Among authors: motoi y. Int Immunol. 2016 May;28(5):211-22. doi: 10.1093/intimm/dxv062. Epub 2015 Oct 20. Int Immunol. 2016. PMID: 26489884 Free PMC article.

8

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.

Tanji H, Ohto U, Motoi Y, Shibata T, Miyake K, Shimizu T. Tanji H, et al. Among authors: motoi y. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3012-7. doi: 10.1073/pnas.1516000113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929371 Free PMC article.

9

The protective effect of the anti-Toll-like receptor 9 antibody against acute cytokine storm caused by immunostimulatory DNA.

Murakami Y, Fukui R, Motoi Y, Shibata T, Saitoh SI, Sato R, Miyake K. Murakami Y, et al. Among authors: motoi y. Sci Rep. 2017 Mar 7;7:44042. doi: 10.1038/srep44042. Sci Rep. 2017. PMID: 28266597 Free PMC article.

10

Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs.

Furusho K, Shibata T, Sato R, Fukui R, Motoi Y, Zhang Y, Saitoh SI, Ichinohe T, Moriyama M, Nakamura S, Miyake K. Furusho K, et al. Among authors: motoi y. Int Immunol. 2019 Mar 5;31(3):167-173. doi: 10.1093/intimm/dxy075. Int Immunol. 2019. PMID: 30535046

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