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Page 1
A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis.
Knevel R, Krabben A, Wilson AG, Brouwer E, Leijsma MK, Lindqvist E, de Rooy DP, Daha NA, van der Linden MP, Tsonaka S, Zhernakova A, Westra HJ, Franke L, Houwing-Duistermaat JJ, Toes RE, Huizinga TW, Saxne T, van der Helm-van Mil AH. Knevel R, et al. Among authors: westra hj. Arthritis Rheum. 2013 Mar;65(3):582-9. doi: 10.1002/art.37808. Arthritis Rheum. 2013. PMID: 23440692 Free article.
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
Cozen W, Timofeeva MN, Li D, Diepstra A, Hazelett D, Delahaye-Sourdeix M, Edlund CK, Franke L, Rostgaard K, Van Den Berg DJ, Cortessis VK, Smedby KE, Glaser SL, Westra HJ, Robison LL, Mack TM, Ghesquieres H, Hwang AE, Nieters A, de Sanjose S, Lightfoot T, Becker N, Maynadie M, Foretova L, Roman E, Benavente Y, Rand KA, Nathwani BN, Glimelius B, Staines A, Boffetta P, Link BK, Kiemeney L, Ansell SM, Bhatia S, Strong LC, Galan P, Vatten L, Habermann TM, Duell EJ, Lake A, Veenstra RN, Visser L, Liu Y, Urayama KY, Montgomery D, Gaborieau V, Weiss LM, Byrnes G, Lathrop M, Cocco P, Best T, Skol AD, Adami HO, Melbye M, Cerhan JR, Gallagher A, Taylor GM, Slager SL, Brennan P, Coetzee GA, Conti DV, Onel K, Jarrett RF, Hjalgrim H, van den Berg A, McKay JD. Cozen W, et al. Among authors: westra hj. Nat Commun. 2014 Jun 12;5:3856. doi: 10.1038/ncomms4856. Nat Commun. 2014. PMID: 24920014 Free PMC article.
Linking the gut microbiome to host DNA methylation by a discovery and replication epigenome-wide association study.
Demirkan A, van Dongen J, Finnicum CT, Westra HJ, Jankipersadsing S, Willemsen G, Ijzerman RG, Boomsma DI, Ehli EA, Bonder MJ, Fu J, Franke L, Wijmenga C, de Geus EJC, Kurilshikov A, Zhernakova A. Demirkan A, et al. Among authors: westra hj. BMC Genomics. 2024 Dec 19;25(1):1224. doi: 10.1186/s12864-024-11136-x. BMC Genomics. 2024. PMID: 39702006 Free PMC article.
Epigenome-wide association study on the plasma metabolome suggests self-regulation of the glycine and serine pathway through DNA methylation.
Wu J, Palasantzas V, Andreu-Sánchez S, Plösch T, Leonard S, Li S, Bonder MJ, Westra HJ, van Meurs J, Ghanbari M, Franke L, Zhernakova A, Fu J, Hoogerland JA, Zhernakova DV. Wu J, et al. Among authors: westra hj. Clin Epigenetics. 2024 Aug 13;16(1):104. doi: 10.1186/s13148-024-01718-7. Clin Epigenetics. 2024. PMID: 39138531 Free PMC article.
Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.
Urzúa-Traslaviña CG, van Lieshout T, Boulogne F, Domanegg K, Zidan M, Bakker OB, Claringbould A, de Ridder J, Zwart W, Westra HJ, Deelen P, Franke L. Urzúa-Traslaviña CG, et al. Among authors: westra hj. BMC Med Genomics. 2024 Jul 15;17(1):186. doi: 10.1186/s12920-024-01941-4. BMC Med Genomics. 2024. PMID: 39010058 Free PMC article.
Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development.
Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, Aguiar VRC, Chiu DJ, Westra HJ, Gutierrez-Arcelus M, Weirauch MT, Raychaudhuri S, Rao DA, Nigrovic PA. Kim T, et al. Among authors: westra hj. Nat Commun. 2024 Mar 9;15(1):2150. doi: 10.1038/s41467-024-46457-8. Nat Commun. 2024. PMID: 38459032 Free PMC article.
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data.
Li S, Schmid KT, de Vries DH, Korshevniuk M, Losert C, Oelen R, van Blokland IV; BIOS Consortium, sc-eQTLgen Consortium; Groot HE, Swertz MA, van der Harst P, Westra HJ, van der Wijst MGP, Heinig M, Franke L. Li S, et al. Among authors: westra hj. Genome Biol. 2023 Apr 18;24(1):80. doi: 10.1186/s13059-023-02897-x. Genome Biol. 2023. PMID: 37072791 Free PMC article.
110 results