Mendez-Alvarez E - Search Results

1

Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.

Pisani L, Barletta M, Soto-Otero R, Nicolotti O, Mendez-Alvarez E, Catto M, Introcaso A, Stefanachi A, Cellamare S, Altomare C, Carotti A. Pisani L, et al. J Med Chem. 2013 Mar 28;56(6):2651-64. doi: 10.1021/jm4000769. Epub 2013 Mar 13. J Med Chem. 2013. PMID: 23437843

2

Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke.

Méndez-Alvarez E, Soto-Otero R, Sánchez-Sellero I, López-Rivadulla Lamas M. Méndez-Alvarez E, et al. Life Sci. 1997;60(19):1719-27. doi: 10.1016/s0024-3205(97)00114-8. Life Sci. 1997. PMID: 9129127

3

Studies on the interaction between 1,2,3,4-tetrahydro-beta-carboline and cigarette smoke: a potential mechanism of neuroprotection for Parkinson's disease.

Soto-Otero R, Méndez-Alvarez E, Riguera-Vega R, Quiñoá-Cabana E, Sánchez-Sellero I, López-Rivadulla Lamas M. Soto-Otero R, et al. Brain Res. 1998 Aug 17;802(1-2):155-62. doi: 10.1016/s0006-8993(98)00538-1. Brain Res. 1998. PMID: 9748553

4

Inhibition of brain monoamine oxidase activity by the generation of hydroxyl radicals: potential implications in relation to oxidative stress.

Soto-Otero R, Méndez-Alvarez E, Hermida-Ameijeiras A, Sánchez-Sellero I, Cruz-Landeira A, Lamas ML. Soto-Otero R, et al. Life Sci. 2001 Jul 13;69(8):879-89. doi: 10.1016/s0024-3205(01)01178-x. Life Sci. 2001. PMID: 11488401

5

Autoxidation and MAO-mediated metabolism of dopamine as a potential cause of oxidative stress: role of ferrous and ferric ions.

Hermida-Ameijeiras A, Méndez-Alvarez E, Sánchez-Iglesias S, Sanmartín-Suárez C, Soto-Otero R. Hermida-Ameijeiras A, et al. Neurochem Int. 2004 Jul;45(1):103-16. doi: 10.1016/j.neuint.2003.11.018. Neurochem Int. 2004. PMID: 15082228

6

A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins.

Santana L, Uriarte E, González-Díaz H, Zagotto G, Soto-Otero R, Méndez-Alvarez E. Santana L, et al. J Med Chem. 2006 Feb 9;49(3):1149-56. doi: 10.1021/jm0509849. J Med Chem. 2006. PMID: 16451079

7

Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism.

Muñoz A, Rey P, Guerra MJ, Mendez-Alvarez E, Soto-Otero R, Labandeira-Garcia JL. Muñoz A, et al. Neuropharmacology. 2006 Jul;51(1):112-20. doi: 10.1016/j.neuropharm.2006.03.004. Epub 2006 May 5. Neuropharmacology. 2006. PMID: 16678218

8

Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors.

Carotti A, de Candia M, Catto M, Borisova TN, Varlamov AV, Méndez-Alvarez E, Soto-Otero R, Voskressensky LG, Altomare C. Carotti A, et al. Bioorg Med Chem. 2006 Nov 1;14(21):7205-12. doi: 10.1016/j.bmc.2006.06.055. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843666

9

Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand- and target-based approaches.

Catto M, Nicolotti O, Leonetti F, Carotti A, Favia AD, Soto-Otero R, Méndez-Alvarez E, Carotti A. Catto M, et al. J Med Chem. 2006 Aug 10;49(16):4912-25. doi: 10.1021/jm060183l. J Med Chem. 2006. PMID: 16884303

10

Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives.

Carotti A, Catto M, Leonetti F, Campagna F, Soto-Otero R, Méndez-Alvarez E, Thull U, Testa B, Altomare C. Carotti A, et al. J Med Chem. 2007 Nov 1;50(22):5364-71. doi: 10.1021/jm070728r. Epub 2007 Oct 2. J Med Chem. 2007. PMID: 17910428

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