Hayashi K - Search Results

1

The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice.

Hasegawa K, Wakino S, Kimoto M, Minakuchi H, Fujimura K, Hosoya K, Komatsu M, Kaneko Y, Kanda T, Tokuyama H, Hayashi K, Itoh H. Hasegawa K, et al. Among authors: hayashi k. FASEB J. 2013 Jun;27(6):2301-15. doi: 10.1096/fj.12-226092. Epub 2013 Feb 21. FASEB J. 2013. PMID: 23430976

2

Rho-kinase as a molecular target for insulin resistance and hypertension.

Kanda T, Wakino S, Homma K, Yoshioka K, Tatematsu S, Hasegawa K, Takamatsu I, Sugano N, Hayashi K, Saruta T. Kanda T, et al. Among authors: hayashi k. FASEB J. 2006 Jan;20(1):169-71. doi: 10.1096/fj.05-4197fje. Epub 2005 Nov 2. FASEB J. 2006. PMID: 16267124

3

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes.

Hasegawa K, Wakino S, Simic P, Sakamaki Y, Minakuchi H, Fujimura K, Hosoya K, Komatsu M, Kaneko Y, Kanda T, Kubota E, Tokuyama H, Hayashi K, Guarente L, Itoh H. Hasegawa K, et al. Among authors: hayashi k. Nat Med. 2013 Nov;19(11):1496-504. doi: 10.1038/nm.3363. Epub 2013 Oct 20. Nat Med. 2013. PMID: 24141423 Free PMC article.

4

Insulin resistance in chronic kidney disease is ameliorated by spironolactone in rats and humans.

Hosoya K, Minakuchi H, Wakino S, Fujimura K, Hasegawa K, Komatsu M, Yoshifuji A, Futatsugi K, Shinozuka K, Washida N, Kanda T, Tokuyama H, Hayashi K, Itoh H. Hosoya K, et al. Among authors: hayashi k. Kidney Int. 2015 Apr;87(4):749-60. doi: 10.1038/ki.2014.348. Epub 2014 Oct 22. Kidney Int. 2015. PMID: 25337775 Free article. Clinical Trial.

5

Role of asymmetrical dimethylarginine in renal microvascular endothelial dysfunction in chronic renal failure with hypertension.

Okubo K, Hayashi K, Wakino S, Matsuda H, Kubota E, Honda M, Tokuyama H, Yamamoto T, Kajiya F, Saruta T. Okubo K, et al. Among authors: hayashi k. Hypertens Res. 2005 Feb;28(2):181-9. doi: 10.1291/hypres.28.181. Hypertens Res. 2005. PMID: 16025746

6

Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats.

Wakino S, Hayashi K, Tatematsu S, Hasegawa K, Takamatsu I, Kanda T, Homma K, Yoshioka K, Sugano N, Saruta T. Wakino S, et al. Among authors: hayashi k. Hypertens Res. 2005 Mar;28(3):255-62. doi: 10.1291/hypres.28.255. Hypertens Res. 2005. PMID: 16097370

7

Dimethylarginine dimethylaminohydrolase 2 increases vascular endothelial growth factor expression through Sp1 transcription factor in endothelial cells.

Hasegawa K, Wakino S, Tanaka T, Kimoto M, Tatematsu S, Kanda T, Yoshioka K, Homma K, Sugano N, Kurabayashi M, Saruta T, Hayashi K. Hasegawa K, et al. Among authors: hayashi k. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1488-94. doi: 10.1161/01.ATV.0000219615.88323.b4. Epub 2006 Mar 30. Arterioscler Thromb Vasc Biol. 2006. PMID: 16574895

8

Role of nitric oxide-producing and -degrading pathways in coronary endothelial dysfunction in chronic kidney disease.

Tatematsu S, Wakino S, Kanda T, Homma K, Yoshioka K, Hasegawa K, Sugano N, Kimoto M, Saruta T, Hayashi K. Tatematsu S, et al. Among authors: hayashi k. J Am Soc Nephrol. 2007 Mar;18(3):741-9. doi: 10.1681/ASN.2006040367. Epub 2007 Jan 31. J Am Soc Nephrol. 2007. PMID: 17267746

9

Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.

Hasegawa K, Wakino S, Tatematsu S, Yoshioka K, Homma K, Sugano N, Kimoto M, Hayashi K, Itoh H. Hasegawa K, et al. Among authors: hayashi k. Circ Res. 2007 Jul 20;101(2):e2-10. doi: 10.1161/CIRCRESAHA.107.156901. Epub 2007 Jun 29. Circ Res. 2007. PMID: 17601800

10

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression.

Hasegawa K, Wakino S, Yoshioka K, Tatematsu S, Hara Y, Minakuchi H, Washida N, Tokuyama H, Hayashi K, Itoh H. Hasegawa K, et al. Among authors: hayashi k. Biochem Biophys Res Commun. 2008 Jul 18;372(1):51-6. doi: 10.1016/j.bbrc.2008.04.176. Epub 2008 May 15. Biochem Biophys Res Commun. 2008. PMID: 18485895

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