Stewart AF - Search Results

1

Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.

Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: stewart af. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.

2

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.

Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: stewart af. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.

3

Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes.

Michurina A, Sakib MS, Kerimoglu C, Krüger DM, Kaurani L, Islam MR, Joshi PD, Schröder S, Centeno TP, Zhou J, Pradhan R, Cha J, Xu X, Eichele G, Zeisberg EM, Kranz A, Stewart AF, Fischer A. Michurina A, et al. Among authors: stewart af. EMBO J. 2022 Jan 4;41(1):e106459. doi: 10.15252/embj.2020106459. Epub 2021 Nov 22. EMBO J. 2022. PMID: 34806773 Free PMC article.

4

Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation.

Hanna CW, Huang J, Belton C, Reinhardt S, Dahl A, Andrews S, Stewart AF, Kranz A, Kelsey G. Hanna CW, et al. Among authors: stewart af. Nucleic Acids Res. 2022 Feb 28;50(4):1993-2004. doi: 10.1093/nar/gkac051. Nucleic Acids Res. 2022. PMID: 35137160 Free PMC article.

5

Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.

Jakovcevski M, Ruan H, Shen EY, Dincer A, Javidfar B, Ma Q, Peter CJ, Cheung I, Mitchell AC, Jiang Y, Lin CL, Pothula V, Stewart AF, Ernst P, Yao WD, Akbarian S. Jakovcevski M, et al. Among authors: stewart af. J Neurosci. 2015 Apr 1;35(13):5097-108. doi: 10.1523/JNEUROSCI.3004-14.2015. J Neurosci. 2015. PMID: 25834037 Free PMC article.

6

The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.

Schmidt K, Zhang Q, Tasdogan A, Petzold A, Dahl A, Arneth BM, Slany R, Fehling HJ, Kranz A, Stewart AF, Anastassiadis K. Schmidt K, et al. Among authors: stewart af. Elife. 2018 Jun 19;7:e27157. doi: 10.7554/eLife.27157. Elife. 2018. PMID: 29916805 Free PMC article.

7

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

Bledau AS, Schmidt K, Neumann K, Hill U, Ciotta G, Gupta A, Torres DC, Fu J, Kranz A, Stewart AF, Anastassiadis K. Bledau AS, et al. Among authors: stewart af. Development. 2014 Mar;141(5):1022-35. doi: 10.1242/dev.098152. Development. 2014. PMID: 24550110

8

Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.

Brici D, Zhang Q, Reinhardt S, Dahl A, Hartmann H, Schmidt K, Goveas N, Huang J, Gahurova L, Kelsey G, Anastassiadis K, Stewart AF, Kranz A. Brici D, et al. Among authors: stewart af. Development. 2017 Jul 15;144(14):2606-2617. doi: 10.1242/dev.143347. Epub 2017 Jun 15. Development. 2017. PMID: 28619824

9

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.

Hanna CW, Taudt A, Huang J, Gahurova L, Kranz A, Andrews S, Dean W, Stewart AF, Colomé-Tatché M, Kelsey G. Hanna CW, et al. Among authors: stewart af. Nat Struct Mol Biol. 2018 Jan;25(1):73-82. doi: 10.1038/s41594-017-0013-5. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323282

10

Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.

Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P. Chen Y, et al. Among authors: stewart af. Exp Hematol. 2019 Jan;69:37-42. doi: 10.1016/j.exphem.2018.10.001. Epub 2018 Oct 10. Exp Hematol. 2019. PMID: 30315824 Free PMC article.

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