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IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells.
Santegoets SJ, Turksma AW, Suhoski MM, Stam AG, Albelda SM, Hooijberg E, Scheper RJ, van den Eertwegh AJ, Gerritsen WR, Powell DJ Jr, June CH, de Gruijl TD. Santegoets SJ, et al. Among authors: hooijberg e. J Transl Med. 2013 Feb 12;11:37. doi: 10.1186/1479-5876-11-37. J Transl Med. 2013. PMID: 23402380 Free PMC article.
In vitro priming of tumor-specific cytotoxic T lymphocytes using allogeneic dendritic cells derived from the human MUTZ-3 cell line.
Santegoets SJ, Schreurs MW, Masterson AJ, Liu YP, Goletz S, Baumeister H, Kueter EW, Lougheed SM, van den Eertwegh AJ, Scheper RJ, Hooijberg E, de Gruijl TD. Santegoets SJ, et al. Among authors: hooijberg e. Cancer Immunol Immunother. 2006 Dec;55(12):1480-90. doi: 10.1007/s00262-006-0142-x. Epub 2006 Feb 9. Cancer Immunol Immunother. 2006. PMID: 16468034 Free PMC article.
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression.
van Houdt IS, Sluijter BJ, Moesbergen LM, Vos WM, de Gruijl TD, Molenkamp BG, van den Eertwegh AJ, Hooijberg E, van Leeuwen PA, Meijer CJ, Oudejans JJ. van Houdt IS, et al. Among authors: hooijberg e. Int J Cancer. 2008 Aug 1;123(3):609-15. doi: 10.1002/ijc.23543. Int J Cancer. 2008. PMID: 18498132
Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus.
Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, van den Tol MP, Hooijberg E, Pereboev A, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: hooijberg e. J Immunother. 2010 Sep;33(7):706-15. doi: 10.1097/CJI.0b013e3181eccbd4. J Immunother. 2010. PMID: 20664356
142 results