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Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.
Jimenez JM, Boyall D, Brenchley G, Collier PN, Davis CJ, Fraysse D, Keily SB, Henderson J, Miller A, Pierard F, Settimo L, Twin HC, Bolton CM, Curnock AP, Chiu P, Tanner AJ, Young S. Jimenez JM, et al. Among authors: chiu p. J Med Chem. 2013 Mar 14;56(5):1799-810. doi: 10.1021/jm301465a. Epub 2013 Feb 11. J Med Chem. 2013. PMID: 23398373
Structure-based optimization of aminopyridines as PKCθ inhibitors.
Jimenez JM, Davis C, Boyall D, Fraysse D, Knegtel R, Settimo L, Young S, Bolton C, Chiu P, Curnock A, Rasmussen R, Tanner A, Ager I. Jimenez JM, et al. Among authors: chiu p. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4645-9. doi: 10.1016/j.bmcl.2012.05.114. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22738630
Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis.
Collier PN, Twin HC, Knegtel RMA, Boyall D, Brenchley G, Davis CJ, Keily S, Mak C, Miller A, Pierard F, Settimo L, Bolton CM, Chiu P, Curnock A, Doyle E, Tanner AJ, Jimenez JM. Collier PN, et al. Among authors: chiu p. ACS Med Chem Lett. 2019 Jun 27;10(8):1134-1139. doi: 10.1021/acsmedchemlett.9b00134. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31417666 Free PMC article.
Emotional words evoke region- and valence-specific patterns of concurrent neuromodulator release in human thalamus and cortex.
Batten SR, Hartle AE, Barbosa LS, Hadj-Amar B, Bang D, Melville N, Twomey T, White JP, Torres A, Celaya X, McClure SM, Brewer GA, Lohrenz T, Kishida KT, Bina RW, Witcher MR, Vannucci M, Casas B, Chiu P, Montague PR, Howe WM. Batten SR, et al. Among authors: chiu p. Cell Rep. 2025 Jan 7;44(1):115162. doi: 10.1016/j.celrep.2024.115162. Online ahead of print. Cell Rep. 2025. PMID: 39786997 Free article.
Selective treatment de-escalation in advanced prostate cancer: have we come full circle?
Chong B, Saad M, Chong TW, Thng J, Tan YG, Tay KJ, Cheng C, Lin PH, Teoh J, Chiu PK, Lawrentschuk N, Eapen R, Murphy D, Chan J, Chua MLK, Tuan J, Yuen J, Kanesvaran R, Chen K. Chong B, et al. Among authors: chiu pk. BJU Int. 2025 Jan 2. doi: 10.1111/bju.16632. Online ahead of print. BJU Int. 2025. PMID: 39748463 Review.
Position statement of the World Endoscopy Organization: Role of endoscopy in screening, diagnosis, and treatment of esophageal superficial squamous neoplasia.
Hassan C, Antonelli G, Chiu PW, Emura F, Goda K, Prasad I, Al Awadhi S, Al Lehibi A, Arantes V, Cerisoli CL, Draganov P, Fleischer D, Fluxá F, Gonzalez N, Inoue H, John S, Kashin S, Khashab M, Kim GH, Kothari S, Ngamruengphong S, Remes-Troche JM, Sharara AI, Shimamura Y, Villa-Gomez G, Wang KK, Wang WL, Yip HC, Sharma P. Hassan C, et al. Among authors: chiu pw. Dig Endosc. 2024 Dec 25. doi: 10.1111/den.14967. Online ahead of print. Dig Endosc. 2024. PMID: 39722219 Review.
1,810 results