Setola V - Search Results

1

Photochemical activation of TRPA1 channels in neurons and animals.

Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. Kokel D, et al. Among authors: setola v. Nat Chem Biol. 2013 Apr;9(4):257-63. doi: 10.1038/nchembio.1183. Epub 2013 Feb 10. Nat Chem Biol. 2013. PMID: 23396078 Free PMC article.

2

Chemical informatics and target identification in a zebrafish phenotypic screen.

Laggner C, Kokel D, Setola V, Tolia A, Lin H, Irwin JJ, Keiser MJ, Cheung CY, Minor DL Jr, Roth BL, Peterson RT, Shoichet BK. Laggner C, et al. Among authors: setola v. Nat Chem Biol. 2011 Dec 18;8(2):144-6. doi: 10.1038/nchembio.732. Nat Chem Biol. 2011. PMID: 22179068 Free PMC article.

3

Ligand discovery from a dopamine D3 receptor homology model and crystal structure.

Carlsson J, Coleman RG, Setola V, Irwin JJ, Fan H, Schlessinger A, Sali A, Roth BL, Shoichet BK. Carlsson J, et al. Among authors: setola v. Nat Chem Biol. 2011 Sep 18;7(11):769-78. doi: 10.1038/nchembio.662. Nat Chem Biol. 2011. PMID: 21926995 Free PMC article.

4

Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.

Whitby LR, Ando Y, Setola V, Vogt PK, Roth BL, Boger DL. Whitby LR, et al. Among authors: setola v. J Am Chem Soc. 2011 Jul 6;133(26):10184-94. doi: 10.1021/ja201878v. Epub 2011 Jun 15. J Am Chem Soc. 2011. PMID: 21609016 Free PMC article.

5

N-tetrahydrothiochromenoisoxazole-1-carboxamides as selective antagonists of cloned human 5-HT2B.

Kwon YJ, Saubern S, Macdonald JM, Huang XP, Setola V, Roth BL. Kwon YJ, et al. Among authors: setola v. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5488-90. doi: 10.1016/j.bmcl.2010.07.074. Epub 2010 Jul 21. Bioorg Med Chem Lett. 2010. PMID: 20692833

6

Why mice are neither miniature humans nor small rats: a cautionary tale involving 5-hydroxytryptamine-6 serotonin receptor species variants.

Setola V, Roth BL. Setola V, et al. Mol Pharmacol. 2003 Dec;64(6):1277-8. doi: 10.1124/mol.64.6.1277. Mol Pharmacol. 2003. PMID: 14645656 Review. No abstract available.

7

Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on 'fen-phen'.

Setola V, Roth BL. Setola V, et al. Expert Opin Drug Metab Toxicol. 2005 Oct;1(3):377-87. doi: 10.1517/17425255.1.3.377. Expert Opin Drug Metab Toxicol. 2005. PMID: 16863450 Review.

8

Neurochemical profiles of some novel psychoactive substances.

Iversen L, Gibbons S, Treble R, Setola V, Huang XP, Roth BL. Iversen L, et al. Among authors: setola v. Eur J Pharmacol. 2013 Jan 30;700(1-3):147-51. doi: 10.1016/j.ejphar.2012.12.006. Epub 2012 Dec 21. Eur J Pharmacol. 2013. PMID: 23261499 Free PMC article.

9

Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.

Huang XP, Mangano T, Hufeisen S, Setola V, Roth BL. Huang XP, et al. Among authors: setola v. Assay Drug Dev Technol. 2010 Dec;8(6):727-42. doi: 10.1089/adt.2010.0331. Assay Drug Dev Technol. 2010. PMID: 21158687 Free PMC article.

10

Automated design of ligands to polypharmacological profiles.

Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, Bickerton GR, Read KD, Wetsel WC, Gilbert IH, Roth BL, Hopkins AL. Besnard J, et al. Among authors: setola v. Nature. 2012 Dec 13;492(7428):215-20. doi: 10.1038/nature11691. Nature. 2012. PMID: 23235874 Free PMC article.

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