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Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. G-Dayanandan N, et al. Among authors: paulsen jl. J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6. J Med Chem. 2014. PMID: 24568657 Free PMC article.
Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation.
Blauvelt ML, Khalili M, Jaung W, Paulsen J, Anderson AC, Brian Wilson S, Howell AR. Blauvelt ML, et al. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6374-6. doi: 10.1016/j.bmcl.2008.10.086. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18993065 Free PMC article.
Interdependence of Inhibitor Recognition in HIV-1 Protease.
Paulsen JL, Leidner F, Ragland DA, Kurt Yilmaz N, Schiffer CA. Paulsen JL, et al. J Chem Theory Comput. 2017 May 9;13(5):2300-2309. doi: 10.1021/acs.jctc.6b01262. Epub 2017 Apr 11. J Chem Theory Comput. 2017. PMID: 28358514 Free PMC article.
Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Matthew AN, Leidner F, Lockbaum GJ, Henes M, Zephyr J, Hou S, Rao DN, Timm J, Rusere LN, Ragland DA, Paulsen JL, Prachanronarong K, Soumana DI, Nalivaika EA, Kurt Yilmaz N, Ali A, Schiffer CA. Matthew AN, et al. Among authors: paulsen jl. Chem Rev. 2021 Mar 24;121(6):3238-3270. doi: 10.1021/acs.chemrev.0c00648. Epub 2021 Jan 7. Chem Rev. 2021. PMID: 33410674 Free PMC article. Review.
28 results