Leconte AM - Search Results

1

A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.

Leconte AM, Dickinson BC, Yang DD, Chen IA, Allen B, Liu DR. Leconte AM, et al. Biochemistry. 2013 Feb 26;52(8):1490-9. doi: 10.1021/bi3016185. Epub 2013 Feb 14. Biochemistry. 2013. PMID: 23360105 Free PMC article.

2

Discovery and biological characterization of geranylated RNA in bacteria.

Dumelin CE, Chen Y, Leconte AM, Chen YG, Liu DR. Dumelin CE, et al. Among authors: leconte am. Nat Chem Biol. 2012 Nov;8(11):913-9. doi: 10.1038/nchembio.1070. Epub 2012 Sep 16. Nat Chem Biol. 2012. PMID: 22983156 Free PMC article.

3

Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution.

Dickinson BC, Leconte AM, Allen B, Esvelt KM, Liu DR. Dickinson BC, et al. Among authors: leconte am. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9007-12. doi: 10.1073/pnas.1220670110. Epub 2013 May 14. Proc Natl Acad Sci U S A. 2013. PMID: 23674678 Free PMC article.

4

Taq DNA Polymerase Mutants and 2'-Modified Sugar Recognition.

Schultz HJ, Gochi AM, Chia HE, Ogonowsky AL, Chiang S, Filipovic N, Weiden AG, Hadley EE, Gabriel SE, Leconte AM. Schultz HJ, et al. Among authors: leconte am. Biochemistry. 2015 Sep 29;54(38):5999-6008. doi: 10.1021/acs.biochem.5b00689. Epub 2015 Sep 14. Biochemistry. 2015. PMID: 26334839

5

Discovery of Red-Shifting Mutations in Firefly Luciferase Using High-Throughput Biochemistry.

Colee CM, Oberlag NM, Simon M, Chapman OS, Flanagan LC, Reid-McLaughlin ES, Gewing-Mullins JA, Maiche S, Patel DF, Cavalcanti ARO, Leconte AM. Colee CM, et al. Among authors: leconte am. Biochemistry. 2024 Mar 19;63(6):733-742. doi: 10.1021/acs.biochem.3c00708. Epub 2024 Mar 4. Biochemistry. 2024. PMID: 38437583 Free PMC article.

6

Statistical Coupling Analysis-Guided Library Design for the Discovery of Mutant Luciferases.

Liu MD, Warner EA, Morrissey CE, Fick CW, Wu TS, Ornelas MY, Ochoa GV, Zhang BS, Rathbun CM, Porterfield WB, Prescher JA, Leconte AM. Liu MD, et al. Among authors: leconte am. Biochemistry. 2018 Feb 6;57(5):663-671. doi: 10.1021/acs.biochem.7b01014. Epub 2017 Dec 28. Biochemistry. 2018. PMID: 29224332 Free PMC article.

7

Accurate and Efficient One-Pot Reverse Transcription and Amplification of 2'-Fluoro-Modified Nucleic Acids by Commercial DNA Polymerases.

Thompson AS, Barrett SE, Weiden AG, Venkatesh A, Seto MKC, Gottlieb SZP, Leconte AM. Thompson AS, et al. Among authors: leconte am. Biochemistry. 2020 Aug 11;59(31):2833-2841. doi: 10.1021/acs.biochem.0c00494. Epub 2020 Jul 27. Biochemistry. 2020. PMID: 32659079

8

Polymerase evolution: efforts toward expansion of the genetic code.

Leconte AM, Chen L, Romesberg FE. Leconte AM, et al. J Am Chem Soc. 2005 Sep 14;127(36):12470-1. doi: 10.1021/ja053322h. J Am Chem Soc. 2005. PMID: 16144377 Free PMC article.

9

Directed evolution of DNA polymerases for next-generation sequencing.

Leconte AM, Patel MP, Sass LE, McInerney P, Jarosz M, Kung L, Bowers JL, Buzby PR, Efcavitch JW, Romesberg FE. Leconte AM, et al. Angew Chem Int Ed Engl. 2010 Aug 9;49(34):5921-4. doi: 10.1002/anie.201001607. Angew Chem Int Ed Engl. 2010. PMID: 20629059 Free PMC article.

10

Design and Discovery of New Combinations of Mutant DNA Polymerases and Modified DNA Substrates.

Rosenblum SL, Weiden AG, Lewis EL, Ogonowsky AL, Chia HE, Barrett SE, Liu MD, Leconte AM. Rosenblum SL, et al. Among authors: leconte am. Chembiochem. 2017 Apr 18;18(8):816-823. doi: 10.1002/cbic.201600701. Epub 2017 Apr 7. Chembiochem. 2017. PMID: 28160372

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