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FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.
Neumann M, Coskun E, Fransecky L, Mochmann LH, Bartram I, Sartangi NF, Heesch S, Gökbuget N, Schwartz S, Brandts C, Schlee C, Haas R, Dührsen U, Griesshammer M, Döhner H, Ehninger G, Burmeister T, Blau O, Thiel E, Hoelzer D, Hofmann WK, Baldus CD. Neumann M, et al. Among authors: mochmann lh. PLoS One. 2013;8(1):e53190. doi: 10.1371/journal.pone.0053190. Epub 2013 Jan 24. PLoS One. 2013. PMID: 23359050 Free PMC article.
Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia.
Kaiser M, Kühnl A, Reins J, Fischer S, Ortiz-Tanchez J, Schlee C, Mochmann LH, Heesch S, Benlasfer O, Hofmann WK, Thiel E, Baldus CD. Kaiser M, et al. Among authors: mochmann lh. Blood Cancer J. 2011 Jul;1(7):e28. doi: 10.1038/bcj.2011.28. Epub 2011 Jul 15. Blood Cancer J. 2011. PMID: 22829184 Free PMC article.
Outlook on PI3K/AKT/mTOR inhibition in acute leukemia.
Fransecky L, Mochmann LH, Baldus CD. Fransecky L, et al. Among authors: mochmann lh. Mol Cell Ther. 2015 Mar 20;3:2. doi: 10.1186/s40591-015-0040-8. eCollection 2015. Mol Cell Ther. 2015. PMID: 26056603 Free PMC article.
Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL.
Fransecky L, Neumann M, Heesch S, Schlee C, Ortiz-Tanchez J, Heller S, Mossner M, Schwartz S, Mochmann LH, Isaakidis K, Bastian L, Kees UR, Herold T, Spiekermann K, Gökbuget N, Baldus CD. Fransecky L, et al. Among authors: mochmann lh. J Hematol Oncol. 2016 Sep 22;9(1):95. doi: 10.1186/s13045-016-0324-8. J Hematol Oncol. 2016. PMID: 27658391 Free PMC article.
Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients.
von der Heide EK, Neumann M, Vosberg S, James AR, Schroeder MP, Ortiz-Tanchez J, Isaakidis K, Schlee C, Luther M, Jöhrens K, Anagnostopoulos I, Mochmann LH, Nowak D, Hofmann WK, Greif PA, Baldus CD. von der Heide EK, et al. Among authors: mochmann lh. Leukemia. 2017 May;31(5):1069-1078. doi: 10.1038/leu.2016.324. Epub 2016 Nov 11. Leukemia. 2017. PMID: 27833093
FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling.
Liebig S, Neumann M, Silva P, Ortiz-Tanchez J, Schulze V, Isaakidis K, Schlee C, Schroeder MP, Beder T, Morris LGT, Chan TA, Bastian L, Burmeister T, Schwartz S, Gökbuget N, Mochmann LH, Baldus CD. Liebig S, et al. Among authors: mochmann lh. Sci Rep. 2023 Jan 18;13(1):972. doi: 10.1038/s41598-023-27792-0. Sci Rep. 2023. PMID: 36653435 Free PMC article.
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