Bentley D - Search Results

1

In vivo evaluation of drug-drug interactions linked to UGT inhibition: the effect of probenecid on dalcetrapib pharmacokinetics.

Aceves Baldó P, Anzures-Cabrera J, Bentley D. Aceves Baldó P, et al. Among authors: bentley d. Int J Clin Pharmacol Ther. 2013 Mar;51(3):215-8. doi: 10.5414/CP201766. Int J Clin Pharmacol Ther. 2013. PMID: 23357838 Clinical Trial.

2

Evidence of a drug-drug interaction linked to inhibition of ester hydrolysis by orlistat.

Bentley D, Young AM, Rowell L, Gross G, Tardio J, Carlile D. Bentley D, et al. J Cardiovasc Pharmacol. 2012 Oct;60(4):390-6. doi: 10.1097/FJC.0b013e31826731ff. J Cardiovasc Pharmacol. 2012. PMID: 22820896 Clinical Trial.

3

Effect of hepatic and renal impairment on the pharmacokinetics of dalcetrapib: altered distribution of the active thiol?

Phelan M, Anzures-Cabrera J, Carlile DJ, Rowell L, Kuhlmann O, Arold G, Robson R, Bentley D. Phelan M, et al. Among authors: bentley d. Clin Pharmacokinet. 2013 Apr;52(4):255-65. doi: 10.1007/s40262-013-0035-z. Clin Pharmacokinet. 2013. PMID: 23400900 Clinical Trial.

4

Clinical Pharmacokinetics and Pharmacodynamics of Dalcetrapib.

Black DM, Bentley D, Chapel S, Lee J, Briggs E, Heinonen T. Black DM, et al. Among authors: bentley d. Clin Pharmacokinet. 2018 Nov;57(11):1359-1367. doi: 10.1007/s40262-018-0656-3. Clin Pharmacokinet. 2018. PMID: 29730761 Free PMC article. Review.

5

Bioequivalence of zonisamide orally dispersible tablet and immediate-release capsule formulations: results from two open-label, randomized-sequence, single-dose, two-period, two-treatment crossover studies in healthy male volunteers.

Maanen Rv, Bentley D. Maanen Rv, et al. Among authors: bentley d. Clin Ther. 2009 Jun;31(6):1244-55. doi: 10.1016/j.clinthera.2009.06.012. Clin Ther. 2009. PMID: 19695391 Clinical Trial.

6

Treatment of low HDL-C subjects with the CETP modulator dalcetrapib increases plasma campesterol only in those without ABCA1 and/or ApoA1 mutations.

Niesor EJ, Kallend D, Bentley D, Kastelein JJ, Kees Hovingh G, Stroes ES. Niesor EJ, et al. Among authors: bentley d. Lipids. 2014 Dec;49(12):1245-9. doi: 10.1007/s11745-014-3956-x. Epub 2014 Oct 4. Lipids. 2014. PMID: 25281277 Clinical Trial.

7

Safety and Pharmacokinetic Characterization of Nacubactam, a Novel β-Lactamase Inhibitor, Alone and in Combination with Meropenem, in Healthy Volunteers.

Mallalieu NL, Winter E, Fettner S, Patel K, Zwanziger E, Attley G, Rodriguez I, Kano A, Salama SM, Bentley D, Geretti AM. Mallalieu NL, et al. Among authors: bentley d. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02229-19. doi: 10.1128/AAC.02229-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32041717 Free PMC article.

8

PKPD and cardiac single cell modeling of a DDI study with a CYP3A4 substrate and itraconazole to quantify the effects on QT interval duration.

Jaminion F, Bentley D, Wang K, Wandel C, Derks M, Diack C. Jaminion F, et al. Among authors: bentley d. J Pharmacokinet Pharmacodyn. 2020 Oct;47(5):447-459. doi: 10.1007/s10928-020-09696-y. Epub 2020 Jun 22. J Pharmacokinet Pharmacodyn. 2020. PMID: 32572738 Clinical Trial.

9

Characterization of the pharmacokinetics of entrectinib and its active M5 metabolite in healthy volunteers and patients with solid tumors.

Meneses-Lorente G, Bentley D, Guerini E, Kowalski K, Chow-Maneval E, Yu L, Brink A, Djebli N, Mercier F, Buchheit V, Phipps A. Meneses-Lorente G, et al. Among authors: bentley d. Invest New Drugs. 2021 Jun;39(3):803-811. doi: 10.1007/s10637-020-01047-5. Epub 2021 Jan 18. Invest New Drugs. 2021. PMID: 33462752 Free PMC article. Clinical Trial.

10

No evidence of QT prolongation with supratherapeutic doses of aleglitazar.

Sturm S, Bentley D, Jordan P, Russell-Yarde F, Ruf T. Sturm S, et al. Among authors: bentley d. J Cardiovasc Pharmacol. 2012 Mar;59(3):288-97. doi: 10.1097/FJC.0b013e3182411e67. J Cardiovasc Pharmacol. 2012. PMID: 22113345 Clinical Trial.

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