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Caspase-11 protects against bacteria that escape the vacuole.
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA. Aachoui Y, et al. Among authors: zak de. Science. 2013 Feb 22;339(6122):975-8. doi: 10.1126/science.1230751. Epub 2013 Jan 24. Science. 2013. PMID: 23348507 Free PMC article.
Systems biology of innate immunity.
Zak DE, Aderem A. Zak DE, et al. Immunol Rev. 2009 Jan;227(1):264-82. doi: 10.1111/j.1600-065X.2008.00721.x. Immunol Rev. 2009. PMID: 19120490 Free PMC article. Review.
A systems view of host defense.
Zak DE, Aderem A. Zak DE, et al. Nat Biotechnol. 2009 Nov;27(11):999-1001. doi: 10.1038/nbt1109-999. Nat Biotechnol. 2009. PMID: 19898453 Free PMC article.
Systems-level analysis of innate immunity.
Zak DE, Tam VC, Aderem A. Zak DE, et al. Annu Rev Immunol. 2014;32:547-77. doi: 10.1146/annurev-immunol-032713-120254. Annu Rev Immunol. 2014. PMID: 24655298 Free PMC article. Review.
A blood RNA signature for tuberculosis disease risk: a prospective cohort study.
Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff THM, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SHE, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups. Zak DE, et al. Lancet. 2016 Jun 4;387(10035):2312-2322. doi: 10.1016/S0140-6736(15)01316-1. Epub 2016 Mar 24. Lancet. 2016. PMID: 27017310 Free PMC article.
Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection.
Torrado E, Fountain JJ, Liao M, Tighe M, Reiley WW, Lai RP, Meintjes G, Pearl JE, Chen X, Zak DE, Thompson EG, Aderem A, Ghilardi N, Solache A, McKinstry KK, Strutt TM, Wilkinson RJ, Swain SL, Cooper AM. Torrado E, et al. Among authors: zak de. J Exp Med. 2015 Aug 24;212(9):1449-63. doi: 10.1084/jem.20141520. Epub 2015 Aug 17. J Exp Med. 2015. PMID: 26282876 Free PMC article. Clinical Trial.
52 results