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Caspase-11 protects against bacteria that escape the vacuole.
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA. Aachoui Y, et al. Among authors: fontana mf. Science. 2013 Feb 22;339(6122):975-8. doi: 10.1126/science.1230751. Epub 2013 Jan 24. Science. 2013. PMID: 23348507 Free PMC article.
Two signal models in innate immunity.
Fontana MF, Vance RE. Fontana MF, et al. Immunol Rev. 2011 Sep;243(1):26-39. doi: 10.1111/j.1600-065X.2011.01037.x. Immunol Rev. 2011. PMID: 21884165
Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Gonçalves AV, Margolis SR, Quirino GFS, Mascarenhas DPA, Rauch I, Nichols RD, Ansaldo E, Fontana MF, Vance RE, Zamboni DS. Gonçalves AV, et al. Among authors: fontana mf. PLoS Pathog. 2019 Jun 28;15(6):e1007886. doi: 10.1371/journal.ppat.1007886. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31251782 Free PMC article.
Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit.
Nadjsombati MS, McGinty JW, Lyons-Cohen MR, Jaffe JB, DiPeso L, Schneider C, Miller CN, Pollack JL, Nagana Gowda GA, Fontana MF, Erle DJ, Anderson MS, Locksley RM, Raftery D, von Moltke J. Nadjsombati MS, et al. Among authors: fontana mf. Immunity. 2018 Jul 17;49(1):33-41.e7. doi: 10.1016/j.immuni.2018.06.016. Immunity. 2018. PMID: 30021144 Free PMC article.
37 results