Xu Y - Search Results

1

Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus.

Xu Y, Espinosa-Artiles P, Schubert V, Xu YM, Zhang W, Lin M, Gunatilaka AA, Süssmuth R, Molnár I. Xu Y, et al. Among authors: xu ym. Appl Environ Microbiol. 2013 Mar;79(6):2038-47. doi: 10.1128/AEM.03334-12. Epub 2013 Jan 18. Appl Environ Microbiol. 2013. PMID: 23335766 Free PMC article.

2

Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis.

Xie L, Zhang L, Wang C, Wang X, Xu YM, Yu H, Wu P, Li S, Han L, Gunatilaka AAL, Wei X, Lin M, Molnár I, Xu Y. Xie L, et al. Among authors: xu ym, xu y. Proc Natl Acad Sci U S A. 2018 May 29;115(22):E4980-E4989. doi: 10.1073/pnas.1716046115. Epub 2018 May 14. Proc Natl Acad Sci U S A. 2018. PMID: 29760061 Free PMC article.

3

Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds.

Wang X, Wang C, Duan L, Zhang L, Liu H, Xu YM, Liu Q, Mao T, Zhang W, Chen M, Lin M, Gunatilaka AAL, Xu Y, Molnár I. Wang X, et al. Among authors: xu ym, xu y. J Am Chem Soc. 2019 Mar 13;141(10):4355-4364. doi: 10.1021/jacs.8b12967. Epub 2019 Feb 27. J Am Chem Soc. 2019. PMID: 30767524 Free PMC article.

4

Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases.

Wang C, Wang X, Zhang L, Yue Q, Liu Q, Xu YM, Gunatilaka AAL, Wei X, Xu Y, Molnár I. Wang C, et al. Among authors: xu ym, xu y. J Am Chem Soc. 2020 Oct 7;142(40):17093-17104. doi: 10.1021/jacs.0c07050. Epub 2020 Sep 23. J Am Chem Soc. 2020. PMID: 32833442 Free PMC article.

5

Structure-activity relationships for withanolides as inducers of the cellular heat-shock response.

Wijeratne EM, Xu YM, Scherz-Shouval R, Marron MT, Rocha DD, Liu MX, Costa-Lotufo LV, Santagata S, Lindquist S, Whitesell L, Gunatilaka AA. Wijeratne EM, et al. J Med Chem. 2014 Apr 10;57(7):2851-63. doi: 10.1021/jm401279n. Epub 2014 Mar 25. J Med Chem. 2014. PMID: 24625088

6

Diversity-Oriented Combinatorial Biosynthesis of Hybrid Polyketide Scaffolds from Azaphilone and Benzenediol Lactone Biosynthons.

Bai J, Lu Y, Xu YM, Zhang W, Chen M, Lin M, Gunatilaka AA, Xu Y, Molnár I. Bai J, et al. Among authors: xu ym, xu y. Org Lett. 2016 Mar 18;18(6):1262-5. doi: 10.1021/acs.orglett.6b00110. Epub 2016 Mar 2. Org Lett. 2016. PMID: 26934205 Free PMC article.

7

Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.

Wijeratne EMK, Oliveira MCF, Mafezoli J, Xu YM, Minguzzi S, Batista PHJ, Pessoa ODL, Whitesell L, Gunatilaka AAL. Wijeratne EMK, et al. J Nat Prod. 2018 Apr 27;81(4):825-837. doi: 10.1021/acs.jnatprod.7b00918. Epub 2018 Mar 14. J Nat Prod. 2018. PMID: 29537263

8

Modulation of polyketide biosynthetic pathway of the endophytic fungus, Anteaglonium sp. FL0768, by copper (II) and anacardic acid.

Mafezoli J, Xu YM, Hilário F, Freidhof B, Espinosa-Artiles P, Dos Santos LC, de Oliveira MCF, Gunatilaka AAL. Mafezoli J, et al. Phytochem Lett. 2018 Dec;28:157-163. doi: 10.1016/j.phytol.2018.10.011. Epub 2018 Oct 25. Phytochem Lett. 2018. PMID: 31354886 Free PMC article.

9

Production and Structural Diversification of Withanolides by Aeroponic Cultivation of Plants of Solanaceae: Cytotoxic and Other Withanolides from Aeroponically Grown Physalis coztomatl.

Xu YM, Wijeratne EMK, Liu MX, Xuan L, Wang W, Gunatilaka AAL. Xu YM, et al. Molecules. 2022 Jan 28;27(3):909. doi: 10.3390/molecules27030909. Molecules. 2022. PMID: 35164184 Free PMC article.

10

Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1).

Xu YM, McLaughlin SP, Gunatilaka AA. Xu YM, et al. J Nat Prod. 2007 Dec;70(12):2045-8. doi: 10.1021/np0704553. Epub 2007 Dec 6. J Nat Prod. 2007. PMID: 18052324

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