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The mitotic kinase Aurora--a promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα(+) breast cancer cells.
D'Assoro AB, Liu T, Quatraro C, Amato A, Opyrchal M, Leontovich A, Ikeda Y, Ohmine S, Lingle W, Suman V, Ecsedy J, Iankov I, Di Leonardo A, Ayers-Inglers J, Degnim A, Billadeau D, McCubrey J, Ingle J, Salisbury JL, Galanis E. D'Assoro AB, et al. Among authors: galanis e. Oncogene. 2014 Jan 30;33(5):599-610. doi: 10.1038/onc.2012.628. Epub 2013 Jan 21. Oncogene. 2014. PMID: 23334326 Free PMC article.
Impaired p53 function leads to centrosome amplification, acquired ERalpha phenotypic heterogeneity and distant metastases in breast cancer MCF-7 xenografts.
D'Assoro AB, Busby R, Acu ID, Quatraro C, Reinholz MM, Farrugia DJ, Schroeder MA, Allen C, Stivala F, Galanis E, Salisbury JL. D'Assoro AB, et al. Among authors: galanis e. Oncogene. 2008 Jun 26;27(28):3901-11. doi: 10.1038/onc.2008.18. Epub 2008 Feb 11. Oncogene. 2008. PMID: 18264135 Free PMC article.
Attenuated oncolytic measles virus strains as cancer therapeutics.
Msaouel P, Iankov ID, Dispenzieri A, Galanis E. Msaouel P, et al. Among authors: galanis e. Curr Pharm Biotechnol. 2012 Jul;13(9):1732-41. doi: 10.2174/138920112800958896. Curr Pharm Biotechnol. 2012. PMID: 21740361 Free PMC article. Review.
ONYX-411, a conditionally replicative oncolytic adenovirus, induces cell death in anaplastic thyroid carcinoma cell lines and suppresses the growth of xenograft tumors in nude mice.
Reddi HV, Madde P, Reichert-Eberhardt AJ, Galanis EC, Copland JA, McIver B, Grebe SK, Eberhardt NL. Reddi HV, et al. Among authors: galanis ec. Cancer Gene Ther. 2008 Nov;15(11):750-7. doi: 10.1038/cgt.2008.44. Epub 2008 Jun 27. Cancer Gene Ther. 2008. PMID: 18583996 Free PMC article.
365 results