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Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
Lygate CA, Aksentijevic D, Dawson D, ten Hove M, Phillips D, de Bono JP, Medway DJ, Sebag-Montefiore L, Hunyor I, Channon KM, Clarke K, Zervou S, Watkins H, Balaban RS, Neubauer S. Lygate CA, et al. Among authors: medway dj. Circ Res. 2013 Mar 15;112(6):945-55. doi: 10.1161/CIRCRESAHA.112.300725. Epub 2013 Jan 16. Circ Res. 2013. PMID: 23325497 Free PMC article.
Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
Lygate CA, Bohl S, ten Hove M, Faller KM, Ostrowski PJ, Zervou S, Medway DJ, Aksentijevic D, Sebag-Montefiore L, Wallis J, Clarke K, Watkins H, Schneider JE, Neubauer S. Lygate CA, et al. Among authors: medway dj. Cardiovasc Res. 2012 Dec 1;96(3):466-75. doi: 10.1093/cvr/cvs272. Epub 2012 Aug 21. Cardiovasc Res. 2012. PMID: 22915766 Free PMC article.
A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis.
Zervou S, Ray T, Sahgal N, Sebag-Montefiore L, Cross R, Medway DJ, Ostrowski PJ, Neubauer S, Lygate CA. Zervou S, et al. Among authors: medway dj. Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E263-70. doi: 10.1152/ajpendo.00637.2012. Epub 2013 May 28. Am J Physiol Endocrinol Metab. 2013. PMID: 23715727 Free PMC article.
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