Liu D - Search Results

1

Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate.

Wu J, Zhang D, Chen L, Li J, Wang J, Ning C, Yu N, Zhao F, Chen D, Chen X, Chen K, Jiang H, Liu H, Liu D. Wu J, et al. Among authors: liu h, liu d. J Med Chem. 2013 Feb 14;56(3):761-80. doi: 10.1021/jm301032j. Epub 2013 Jan 28. J Med Chem. 2013. PMID: 23316803

2

A fluorometric assay of SIRT1 deacetylation activity through quantification of nicotinamide adenine dinucleotide.

Feng Y, Wu J, Chen L, Luo C, Shen X, Chen K, Jiang H, Liu D. Feng Y, et al. Among authors: liu d. Anal Biochem. 2009 Dec 15;395(2):205-10. doi: 10.1016/j.ab.2009.08.011. Epub 2009 Aug 13. Anal Biochem. 2009. PMID: 19682970

3

Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: binding mode, inhibitory mechanism and biological action.

Wu J, Li Y, Chen K, Jiang H, Xu MH, Liu D. Wu J, et al. Among authors: liu d. Eur J Med Chem. 2013 Feb;60:441-50. doi: 10.1016/j.ejmech.2012.12.026. Epub 2012 Dec 20. Eur J Med Chem. 2013. PMID: 23318905

4

Structure-activity relationship and interaction studies of new SIRT1 inhibitors with the scaffold of 3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole.

Wu J, Li J, Xu MH, Liu D. Wu J, et al. Among authors: liu d. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3050-6. doi: 10.1016/j.bmcl.2014.05.028. Epub 2014 May 20. Bioorg Med Chem Lett. 2014. PMID: 24880902

5

A new assay based on fluorescence resonance energy transfer to determine the binding affinity of Bcl-xL inhibitors.

Feng Y, Shen X, Chen K, Jiang H, Liu D. Feng Y, et al. Among authors: liu d. Biosci Biotechnol Biochem. 2008 Jul;72(7):1936-9. doi: 10.1271/bbb.70735. Epub 2008 Jul 7. Biosci Biotechnol Biochem. 2008. PMID: 18603801 Free article.

6

Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1.

Chen L, Feng Y, Zhou Y, Zhu W, Shen X, Chen K, Jiang H, Liu D. Chen L, et al. Among authors: liu d. J Inorg Biochem. 2010 Feb;104(2):180-5. doi: 10.1016/j.jinorgbio.2009.10.021. Epub 2009 Oct 29. J Inorg Biochem. 2010. PMID: 19923004

7

Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

Feng Y, Ding X, Chen T, Chen L, Liu F, Jia X, Luo X, Shen X, Chen K, Jiang H, Wang H, Liu H, Liu D. Feng Y, et al. Among authors: liu h, liu f, liu d. J Med Chem. 2010 May 13;53(9):3465-79. doi: 10.1021/jm901004c. J Med Chem. 2010. PMID: 20405848

8

Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors.

Zhou Y, Jiang C, Zhang Y, Liang Z, Liu W, Wang L, Luo C, Zhong T, Sun Y, Zhao L, Xie X, Jiang H, Zhou N, Liu D, Liu H. Zhou Y, et al. Among authors: liu h, liu w, liu d. J Med Chem. 2010 Aug 12;53(15):5449-66. doi: 10.1021/jm1000584. J Med Chem. 2010. PMID: 20684593

9

Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol.

Cao D, Wang M, Qiu X, Liu D, Jiang H, Yang N, Xu RM. Cao D, et al. Among authors: liu d. Genes Dev. 2015 Jun 15;29(12):1316-25. doi: 10.1101/gad.265462.115. Genes Dev. 2015. PMID: 26109052 Free PMC article.

10

Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors.

Li C, Hu SS, Yang L, Wang M, Long JD, Wang B, Han H, Zhu H, Zhao S, Liu JG, Liu D, Liu H. Li C, et al. Among authors: liu h, liu jg, liu d. ACS Med Chem Lett. 2021 Mar 1;12(3):397-403. doi: 10.1021/acsmedchemlett.0c00559. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738067 Free PMC article.

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