Engen JR - Search Results

1

Structure and dynamic regulation of Abl kinases.

Panjarian S, Iacob RE, Chen S, Engen JR, Smithgall TE. Panjarian S, et al. Among authors: engen jr. J Biol Chem. 2013 Feb 22;288(8):5443-50. doi: 10.1074/jbc.R112.438382. Epub 2013 Jan 11. J Biol Chem. 2013. PMID: 23316053 Free PMC article. Review.

2

Identification and localization of slow, natural, cooperative unfolding in the hematopoietic cell kinase SH3 domain by amide hydrogen exchange and mass spectrometry.

Engen JR, Smithgall TE, Gmeiner WH, Smith DL. Engen JR, et al. Biochemistry. 1997 Nov 25;36(47):14384-91. doi: 10.1021/bi971635m. Biochemistry. 1997. PMID: 9398156

3

Comparison of SH3 and SH2 domain dynamics when expressed alone or in an SH(3+2) construct: the role of protein dynamics in functional regulation.

Engen JR, Smithgall TE, Gmeiner WH, Smith DL. Engen JR, et al. J Mol Biol. 1999 Apr 2;287(3):645-56. doi: 10.1006/jmbi.1999.2619. J Mol Biol. 1999. PMID: 10092465

4

Hydrogen exchange shows peptide binding stabilizes motions in Hck SH2.

Engen JR, Gmeiner WH, Smithgall TE, Smith DL. Engen JR, et al. Biochemistry. 1999 Jul 13;38(28):8926-35. doi: 10.1021/bi982611y. Biochemistry. 1999. PMID: 10413466

5

Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP.

Gmeiner WH, Xu I, Horita DA, Smithgall TE, Engen JR, Smith DL, Byrd RA. Gmeiner WH, et al. Among authors: engen jr. Cell Biochem Biophys. 2001;35(2):115-26. doi: 10.1385/cbb:35:2:115. Cell Biochem Biophys. 2001. PMID: 11892787

6

Regulation of c-Fes tyrosine kinase activity by coiled-coil and SH2 domains: analysis with Saccharomyces cerevisiae.

Takashima Y, Delfino FJ, Engen JR, Superti-Furga G, Smithgall TE. Takashima Y, et al. Among authors: engen jr. Biochemistry. 2003 Apr 1;42(12):3567-74. doi: 10.1021/bi0272499. Biochemistry. 2003. PMID: 12653561

7

Activation of the Src family kinase Hck without SH3-linker release.

Lerner EC, Trible RP, Schiavone AP, Hochrein JM, Engen JR, Smithgall TE. Lerner EC, et al. Among authors: engen jr. J Biol Chem. 2005 Dec 9;280(49):40832-7. doi: 10.1074/jbc.M508782200. Epub 2005 Oct 6. J Biol Chem. 2005. PMID: 16210316 Free article.

8

An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry.

Hochrein JM, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. Hochrein JM, et al. Among authors: engen jr. Protein Sci. 2006 Jan;15(1):65-73. doi: 10.1110/ps.051782206. Epub 2005 Dec 1. Protein Sci. 2006. PMID: 16322569 Free PMC article.

9

Conformational features of the full-length HIV and SIV Nef proteins determined by mass spectrometry.

Hochrein JM, Wales TE, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. Hochrein JM, et al. Among authors: engen jr. Biochemistry. 2006 Jun 27;45(25):7733-9. doi: 10.1021/bi060438x. Biochemistry. 2006. PMID: 16784224

10

Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity.

Meyn MA 3rd, Wilson MB, Abdi FA, Fahey N, Schiavone AP, Wu J, Hochrein JM, Engen JR, Smithgall TE. Meyn MA 3rd, et al. Among authors: engen jr. J Biol Chem. 2006 Oct 13;281(41):30907-16. doi: 10.1074/jbc.M605902200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912036 Free article.

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