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Page 1
Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.
Sidduri A, Tilley JW, Lou J, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Sidduri A, et al. Among authors: renzetti l. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1026-31. doi: 10.1016/j.bmcl.2012.12.026. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312474
Identification of N-acyl 4-(3-pyridonyl)phenylalanine derivatives and their orally active prodrug esters as dual acting α4β1 and α4β7 receptor antagonists.
Tilley JW, Sidduri A, Lou J, Kaplan G, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Tilley JW, et al. Among authors: renzetti l. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1036-40. doi: 10.1016/j.bmcl.2012.12.019. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312471
N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Hull K, Lou JP, Kaplan G, Sheffron A, Chen L, Campbell R, Guthrie R, Huang TN, Huby N, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: renzetti lm. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2475-8. doi: 10.1016/s0960-894x(02)00386-4. Bioorg Med Chem Lett. 2002. PMID: 12161161
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Lou JP, Chen L, Kaplan G, Mennona F, Campbell R, Guthrie R, Huang TN, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: renzetti lm. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82. doi: 10.1016/s0960-894x(02)00387-6. Bioorg Med Chem Lett. 2002. PMID: 12161162
Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Goodnow RA Jr, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Hermann G, Venkat R, Mancebo H, Renzetti LM. Goodnow RA Jr, et al. Among authors: renzetti lm. J Med Chem. 2010 May 13;53(9):3502-16. doi: 10.1021/jm1001919. J Med Chem. 2010. PMID: 20380377
Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.
Hicks A, Goodnow R Jr, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Kowalczyk A, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Benson J, March T, Venkat R, Mancebo H, Renzetti LM. Hicks A, et al. Among authors: renzetti lm. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):33-43. doi: 10.1016/j.prostaglandins.2010.02.003. Epub 2010 Mar 7. Prostaglandins Other Lipid Mediat. 2010. PMID: 20214997
Dual bronchodilatory and pulmonary anti-inflammatory activity of RO5024118, a novel agonist at vasoactive intestinal peptide VPAC2 receptors.
Tannu SA, Renzetti LM, Tare N, Ventre JD, Lavelle D, Lin TA, Morschauser A, Paciorek J, Bolin DR, Michel H, Singer L, Hargaden M, Knowles I, Gardiner P, Cazzola M, Calzetta L, Matera MG, Hicks A. Tannu SA, et al. Among authors: renzetti lm. Br J Pharmacol. 2010 Nov;161(6):1329-42. doi: 10.1111/j.1476-5381.2010.00975.x. Br J Pharmacol. 2010. PMID: 20735404 Free PMC article.
34 results