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Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane.
Schachtner H, Calaminus SD, Sinclair A, Monypenny J, Blundell MP, Leon C, Holyoake TL, Thrasher AJ, Michie AM, Vukovic M, Gachet C, Jones GE, Thomas SG, Watson SP, Machesky LM. Schachtner H, et al. Among authors: gachet c. Blood. 2013 Mar 28;121(13):2542-52. doi: 10.1182/blood-2012-07-443457. Epub 2013 Jan 10. Blood. 2013. PMID: 23305739 Free article.
Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
Tolhurst G, Vial C, Léon C, Gachet C, Evans RJ, Mahaut-Smith MP. Tolhurst G, et al. Among authors: gachet c. Blood. 2005 Sep 1;106(5):1644-51. doi: 10.1182/blood-2005-02-0725. Epub 2005 May 24. Blood. 2005. PMID: 15914557 Free article.
The platelet P2 receptors in arterial thrombosis.
Gachet C, Léon C, Hechler B. Gachet C, et al. Blood Cells Mol Dis. 2006 Mar-Apr;36(2):223-7. doi: 10.1016/j.bcmd.2005.12.024. Epub 2006 Feb 8. Blood Cells Mol Dis. 2006. PMID: 16466948 Review.
Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.
Léon C, Eckly A, Hechler B, Aleil B, Freund M, Ravanat C, Jourdain M, Nonne C, Weber J, Tiedt R, Gratacap MP, Severin S, Cazenave JP, Lanza F, Skoda R, Gachet C. Léon C, et al. Among authors: gachet c. Blood. 2007 Nov 1;110(9):3183-91. doi: 10.1182/blood-2007-03-080184. Epub 2007 Jul 30. Blood. 2007. PMID: 17664350 Free article.
337 results