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Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.
Jacobson LS, Lima H Jr, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Jacobson LS, et al. Among authors: sutterwala fs. J Biol Chem. 2013 Mar 15;288(11):7481-7491. doi: 10.1074/jbc.M112.400655. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23297415 Free PMC article.
Mechanism of NLRP3 inflammasome activation.
Sutterwala FS, Haasken S, Cassel SL. Sutterwala FS, et al. Ann N Y Acad Sci. 2014 Jun;1319(1):82-95. doi: 10.1111/nyas.12458. Epub 2014 May 19. Ann N Y Acad Sci. 2014. PMID: 24840700 Free PMC article. Review.
Control of innate and adaptive immunity by the inflammasome.
Ciraci C, Janczy JR, Sutterwala FS, Cassel SL. Ciraci C, et al. Among authors: sutterwala fs. Microbes Infect. 2012 Nov;14(14):1263-70. doi: 10.1016/j.micinf.2012.07.007. Epub 2012 Jul 24. Microbes Infect. 2012. PMID: 22841804 Free PMC article. Review.
Immune complexes inhibit IL-1 secretion and inflammasome activation.
Janczy JR, Ciraci C, Haasken S, Iwakura Y, Olivier AK, Cassel SL, Sutterwala FS. Janczy JR, et al. Among authors: sutterwala fs. J Immunol. 2014 Nov 15;193(10):5190-8. doi: 10.4049/jimmunol.1400628. Epub 2014 Oct 15. J Immunol. 2014. PMID: 25320279 Free PMC article.
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome.
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, Sutterwala FS. Iyer SS, et al. Among authors: sutterwala fs. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20388-93. doi: 10.1073/pnas.0908698106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918053 Free PMC article.
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS. Iyer SS, et al. Among authors: sutterwala fs. Immunity. 2013 Aug 22;39(2):311-323. doi: 10.1016/j.immuni.2013.08.001. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954133 Free PMC article.
The NLRP3 inflammasome: a sensor of immune danger signals.
Cassel SL, Joly S, Sutterwala FS. Cassel SL, et al. Among authors: sutterwala fs. Semin Immunol. 2009 Aug;21(4):194-8. doi: 10.1016/j.smim.2009.05.002. Epub 2009 Jun 5. Semin Immunol. 2009. PMID: 19501527 Free PMC article. Review.
117 results