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Page 1
Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.
Jacobson LS, Lima H Jr, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Jacobson LS, et al. Among authors: brummelkamp tr. J Biol Chem. 2013 Mar 15;288(11):7481-7491. doi: 10.1074/jbc.M112.400655. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23297415 Free PMC article.
Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation.
Liu JCY, Ackermann L, Hoffmann S, Gál Z, Hendriks IA, Jain C, Morlot L, Tatham MH, McLelland GL, Hay RT, Nielsen ML, Brummelkamp T, Haahr P, Mailand N. Liu JCY, et al. Nat Struct Mol Biol. 2024 Sep;31(9):1355-1367. doi: 10.1038/s41594-024-01294-7. Epub 2024 Apr 22. Nat Struct Mol Biol. 2024. PMID: 38649616 Free PMC article.
Generation of iPSCs from cultured human malignant cells.
Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Carette JE, et al. Among authors: brummelkamp tr. Blood. 2010 May 20;115(20):4039-42. doi: 10.1182/blood-2009-07-231845. Epub 2010 Mar 16. Blood. 2010. PMID: 20233975 Free PMC article.
Ebola virus entry requires the host-programmed recognition of an intracellular receptor.
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Miller EH, et al. Among authors: brummelkamp tr. EMBO J. 2012 Apr 18;31(8):1947-60. doi: 10.1038/emboj.2012.53. Epub 2012 Mar 6. EMBO J. 2012. PMID: 22395071 Free PMC article.
Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.
Jae LT, Raaben M, Riemersma M, van Beusekom E, Blomen VA, Velds A, Kerkhoven RM, Carette JE, Topaloglu H, Meinecke P, Wessels MW, Lefeber DJ, Whelan SP, van Bokhoven H, Brummelkamp TR. Jae LT, et al. Among authors: brummelkamp tr. Science. 2013 Apr 26;340(6131):479-83. doi: 10.1126/science.1233675. Epub 2013 Mar 21. Science. 2013. PMID: 23519211 Free PMC article.
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity.
Winter GE, Radic B, Mayor-Ruiz C, Blomen VA, Trefzer C, Kandasamy RK, Huber KVM, Gridling M, Chen D, Klampfl T, Kralovics R, Kubicek S, Fernandez-Capetillo O, Brummelkamp TR, Superti-Furga G. Winter GE, et al. Among authors: brummelkamp tr. Nat Chem Biol. 2014 Sep;10(9):768-773. doi: 10.1038/nchembio.1590. Epub 2014 Jul 27. Nat Chem Biol. 2014. PMID: 25064833 Free PMC article.
Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.
Herbert AS, Davidson C, Kuehne AI, Bakken R, Braigen SZ, Gunn KE, Whelan SP, Brummelkamp TR, Twenhafel NA, Chandran K, Walkley SU, Dye JM. Herbert AS, et al. Among authors: brummelkamp tr. mBio. 2015 May 26;6(3):e00565-15. doi: 10.1128/mBio.00565-15. mBio. 2015. PMID: 26015498 Free PMC article.
109 results