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Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines.
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, Meitzler JL, Hollingshead M, Haines DC, Butcher D, Roy K, Doroshow JH. Wu Y, et al. Among authors: juhasz a. J Immunol. 2013 Feb 15;190(4):1859-72. doi: 10.4049/jimmunol.1201725. Epub 2013 Jan 7. J Immunol. 2013. PMID: 23296709 Free PMC article.
Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel.
Doroshow JH, Juhasz A, Ge Y, Holbeck S, Lu J, Antony S, Wu Y, Jiang G, Roy K. Doroshow JH, et al. Among authors: juhasz a. Biochem Pharmacol. 2012 May 1;83(9):1195-207. doi: 10.1016/j.bcp.2012.01.022. Epub 2012 Jan 24. Biochem Pharmacol. 2012. PMID: 22305747 Free PMC article.
NADPH oxidases and cancer.
Roy K, Wu Y, Meitzler JL, Juhasz A, Liu H, Jiang G, Lu J, Antony S, Doroshow JH. Roy K, et al. Among authors: juhasz a. Clin Sci (Lond). 2015 Jun;128(12):863-75. doi: 10.1042/CS20140542. Clin Sci (Lond). 2015. PMID: 25818486 Review.
Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A.
Wu Y, Meitzler JL, Antony S, Juhasz A, Lu J, Jiang G, Liu H, Hollingshead M, Haines DC, Butcher D, Panter MS, Roy K, Doroshow JH. Wu Y, et al. Among authors: juhasz a. Oncotarget. 2016 Oct 18;7(42):68412-68433. doi: 10.18632/oncotarget.12032. Oncotarget. 2016. PMID: 27637085 Free PMC article.
620 results