Luu KT - Search Results

1

Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab.

Fayad L, Offner F, Smith MR, Verhoef G, Johnson P, Kaufman JL, Rohatiner A, Advani A, Foran J, Hess G, Coiffier B, Czuczman M, Giné E, Durrant S, Kneissl M, Luu KT, Hua SY, Boni J, Vandendries E, Dang NH. Fayad L, et al. Among authors: luu kt. J Clin Oncol. 2013 Feb 10;31(5):573-83. doi: 10.1200/JCO.2012.42.7211. Epub 2013 Jan 7. J Clin Oncol. 2013. PMID: 23295790 Free PMC article. Clinical Trial.

2

A method for optimizing dosage regimens in oncology by visualizing the safety and efficacy response surface: analysis of inotuzumab ozogamicin.

Luu KT, Boni J. Luu KT, et al. Cancer Chemother Pharmacol. 2016 Oct;78(4):697-708. doi: 10.1007/s00280-016-3118-3. Epub 2016 Aug 4. Cancer Chemother Pharmacol. 2016. PMID: 27491482 Clinical Trial.

3

Population Pharmacokinetics of Nusinersen in the Cerebral Spinal Fluid and Plasma of Pediatric Patients With Spinal Muscular Atrophy Following Intrathecal Administrations.

Luu KT, Norris DA, Gunawan R, Henry S, Geary R, Wang Y. Luu KT, et al. J Clin Pharmacol. 2017 Aug;57(8):1031-1041. doi: 10.1002/jcph.884. Epub 2017 Mar 29. J Clin Pharmacol. 2017. PMID: 28369979

4

A model-based approach to predicting the human pharmacokinetics of a monoclonal antibody exhibiting target-mediated drug disposition.

Luu KT, Bergqvist S, Chen E, Hu-Lowe D, Kraynov E. Luu KT, et al. J Pharmacol Exp Ther. 2012 Jun;341(3):702-8. doi: 10.1124/jpet.112.191999. Epub 2012 Mar 13. J Pharmacol Exp Ther. 2012. PMID: 22414855 Free article.

5

Modeling, simulation, and translation framework for the preclinical development of monoclonal antibodies.

Luu KT, Kraynov E, Kuang B, Vicini P, Zhong WZ. Luu KT, et al. AAPS J. 2013 Apr;15(2):551-8. doi: 10.1208/s12248-013-9464-8. Epub 2013 Feb 14. AAPS J. 2013. PMID: 23408094 Free PMC article. Review.

6

Pharmacokinetic-pharmacodynamic and response sensitization modeling of the intraocular pressure-lowering effect of the EP4 Agonist 5-{3-[(2S)-2-{(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenyl]butyl}-5-oxopyrrolidin-1-yl]propyl}thiophene-2-carboxylate (PF-04475270).

Luu KT, Zhang EY, Prasanna G, Xiang C, Anderson S, Fortner J, Vicini P. Luu KT, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):627-35. doi: 10.1124/jpet.109.157800. Epub 2009 Aug 18. J Pharmacol Exp Ther. 2009. PMID: 19690190

7

A model-based meta-analysis of the effect of latanoprost chronotherapy on the circadian intraocular pressure of patients with glaucoma or ocular hypertension.

Luu KT, Raber SR, Nickens DJ, Vicini P. Luu KT, et al. Clin Pharmacol Ther. 2010 Apr;87(4):421-5. doi: 10.1038/clpt.2009.306. Epub 2010 Feb 17. Clin Pharmacol Ther. 2010. PMID: 20164834

8

Population pharmacokinetics and pharmacodynamics of IONIS-GCGR_Rx, an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model.

Luu KT, Morgan ES, Bhanot S, Geary R, Smith A, Bethune C, Watts L, Henry S, Wang Y. Luu KT, et al. J Pharmacokinet Pharmacodyn. 2017 Jun;44(3):179-191. doi: 10.1007/s10928-017-9505-5. Epub 2017 Jan 28. J Pharmacokinet Pharmacodyn. 2017. PMID: 28132162 Clinical Trial.

9

A Mechanistic and Translational Pharmacokinetic-Pharmacodynamic Model of Abicipar Pegol and Vascular Endothelial Growth Factor Inhibition.

Luu KT, Seal JR, Attar M. Luu KT, et al. J Pharmacol Exp Ther. 2020 May;373(2):184-192. doi: 10.1124/jpet.119.263178. Epub 2020 Feb 25. J Pharmacol Exp Ther. 2020. PMID: 32098861

10

Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials.

Tamhane M, Luu KT, Attar M. Tamhane M, et al. Among authors: luu kt. J Pharmacol Exp Ther. 2021 Sep;378(3):207-214. doi: 10.1124/jpet.120.000483. Epub 2021 Jul 1. J Pharmacol Exp Ther. 2021. PMID: 34210753

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