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Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE. Deelen J, et al. Among authors: de craen aj, de geus ej. Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6. Aging Cell. 2011. PMID: 21418511 Free PMC article.
Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals.
Akintola AA, Noordam R, Jansen SW, de Craen AJ, Ballieux BE, Cobbaert CM, Mooijaart SP, Pijl H, Westendorp RG, van Heemst D. Akintola AA, et al. Among authors: de craen aj. PLoS One. 2015 Oct 7;10(10):e0139973. doi: 10.1371/journal.pone.0139973. eCollection 2015. PLoS One. 2015. PMID: 26445499 Free PMC article.
Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study.
Rozing MP, Westendorp RG, de Craen AJ, Frölich M, Heijmans BT, Beekman M, Wijsman C, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study (LLS) Group. Rozing MP, et al. Among authors: de craen aj. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):365-8. doi: 10.1093/gerona/glp200. Epub 2009 Dec 16. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20018826
Human insulin/IGF-1 and familial longevity at middle age.
Rozing MP, Westendorp RG, Frölich M, de Craen AJ, Beekman M, Heijmans BT, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study (LLS) Group. Rozing MP, et al. Among authors: de craen aj. Aging (Albany NY). 2009 Jul 24;1(8):714-22. doi: 10.18632/aging.100071. Aging (Albany NY). 2009. PMID: 20157552 Free PMC article.
High serum glucose levels are associated with a higher perceived age.
Noordam R, Gunn DA, Tomlin CC, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ, van Heemst D; Leiden Longevity Study Group. Noordam R, et al. Among authors: de craen aj. Age (Dordr). 2013 Feb;35(1):189-95. doi: 10.1007/s11357-011-9339-9. Epub 2011 Nov 20. Age (Dordr). 2013. PMID: 22102339 Free PMC article.
The number of p16INK4a positive cells in human skin reflects biological age.
Waaijer ME, Parish WE, Strongitharm BH, van Heemst D, Slagboom PE, de Craen AJ, Sedivy JM, Westendorp RG, Gunn DA, Maier AB. Waaijer ME, et al. Among authors: de craen aj. Aging Cell. 2012 Aug;11(4):722-5. doi: 10.1111/j.1474-9726.2012.00837.x. Epub 2012 Jun 11. Aging Cell. 2012. PMID: 22612594 Free PMC article.
Brain tissue volumes in familial longevity: the Leiden Longevity Study.
Altmann-Schneider I, de Craen AJ, Slagboom PE, Westendorp RG, van Buchem MA, Maier AB, van der Grond J. Altmann-Schneider I, et al. Among authors: de craen aj. Aging Cell. 2012 Dec;11(6):933-9. doi: 10.1111/j.1474-9726.2012.00868.x. Epub 2012 Sep 4. Aging Cell. 2012. PMID: 22882385 Free article.
464 results