Thomas CJ - Search Results

1

Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.

Duveau DY, Hu X, Walsh MJ, Shukla S, Skoumbourdis AP, Boxer MB, Ambudkar SV, Shen M, Thomas CJ. Duveau DY, et al. Among authors: thomas cj. Bioorg Med Chem Lett. 2013 Feb 1;23(3):682-6. doi: 10.1016/j.bmcl.2012.11.111. Epub 2012 Dec 10. Bioorg Med Chem Lett. 2013. PMID: 23273517 Free PMC article.

2

1-(Phenyl)isoquinoline carboxamides: a novel class of subtype selective inhibitors of thyrotropin-releasing hormone (TRH) receptors.

Jiang JK, Thomas CJ, Neumann S, Lu X, Rice KC, Gershengorn MC. Jiang JK, et al. Among authors: thomas cj. Bioorg Med Chem Lett. 2005 Feb 1;15(3):733-6. doi: 10.1016/j.bmcl.2004.11.017. Bioorg Med Chem Lett. 2005. PMID: 15664847

3

Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry.

Perreira M, Kim EJ, Thomas CJ, Hanover JA. Perreira M, et al. Among authors: thomas cj. Bioorg Med Chem. 2006 Feb 1;14(3):837-46. doi: 10.1016/j.bmc.2005.09.013. Epub 2005 Oct 7. Bioorg Med Chem. 2006. PMID: 16214344

4

The inhibition and treatment of breast cancer with poly (ADP-ribose) polymerase (PARP-1) inhibitors.

De Soto JA, Wang X, Tominaga Y, Wang RH, Cao L, Qiao W, Li C, Xu X, Skoumbourdis AP, Prindiville SA, Thomas CJ, Deng CX. De Soto JA, et al. Among authors: thomas cj. Int J Biol Sci. 2006;2(4):179-85. doi: 10.7150/ijbs.2.179. Epub 2006 Jun 10. Int J Biol Sci. 2006. PMID: 16810332 Free PMC article.

5

N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease.

Huang W, Zheng W, Urban DJ, Inglese J, Sidransky E, Austin CP, Thomas CJ. Huang W, et al. Among authors: thomas cj. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5783-9. doi: 10.1016/j.bmcl.2007.08.050. Epub 2007 Aug 28. Bioorg Med Chem Lett. 2007. PMID: 17827006 Free PMC article.

6

Identification of a potent new chemotype for the selective inhibition of PDE4.

Skoumbourdis AP, Huang R, Southall N, Leister W, Guo V, Cho MH, Inglese J, Nirenberg M, Austin CP, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: thomas cj. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1297-303. doi: 10.1016/j.bmcl.2008.01.028. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18243697 Free PMC article.

7

A virtual screen for diverse ligands: discovery of selective G protein-coupled receptor antagonists.

Engel S, Skoumbourdis AP, Childress J, Neumann S, Deschamps JR, Thomas CJ, Colson AO, Costanzi S, Gershengorn MC. Engel S, et al. Among authors: thomas cj. J Am Chem Soc. 2008 Apr 16;130(15):5115-23. doi: 10.1021/ja077620l. Epub 2008 Mar 22. J Am Chem Soc. 2008. PMID: 18357984

8

Synthesis of Substituted 2-phenylhistamines via a Microwave Promoted Suzuki Coupling.

Skoumbourdis AP, Moore S, Landsman M, Thomas CJ. Skoumbourdis AP, et al. Among authors: thomas cj. Tetrahedron Lett. 2007 Dec 24;48(52):9140-9143. doi: 10.1016/j.tetlet.2007.10.119. Tetrahedron Lett. 2007. PMID: 19112479 Free PMC article.

9

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.

Skoumbourdis AP, Leclair CA, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin CP, Michnick SW, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: thomas cj. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92. doi: 10.1016/j.bmcl.2009.01.057. Epub 2009 Jan 23. Bioorg Med Chem Lett. 2009. PMID: 19464886 Free PMC article.

10

Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.

Zhu PJ, Hobson JP, Southall N, Qiu C, Thomas CJ, Lu J, Inglese J, Zheng W, Leppla SH, Bugge TH, Austin CP, Liu S. Zhu PJ, et al. Among authors: thomas cj. Bioorg Med Chem. 2009 Jul 15;17(14):5139-45. doi: 10.1016/j.bmc.2009.05.054. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19540764 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

547 results

Search Page

Filters