Chen PP - Search Results

1

Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice.

Ma QL, Zuo X, Yang F, Ubeda OJ, Gant DJ, Alaverdyan M, Teng E, Hu S, Chen PP, Maiti P, Teter B, Cole GM, Frautschy SA. Ma QL, et al. Among authors: chen pp. J Biol Chem. 2013 Feb 8;288(6):4056-65. doi: 10.1074/jbc.M112.393751. Epub 2012 Dec 21. J Biol Chem. 2013. PMID: 23264626 Free PMC article.

2

Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

Ma QL, Yang F, Rosario ER, Ubeda OJ, Beech W, Gant DJ, Chen PP, Hudspeth B, Chen C, Zhao Y, Vinters HV, Frautschy SA, Cole GM. Ma QL, et al. Among authors: chen pp, chen c. J Neurosci. 2009 Jul 15;29(28):9078-89. doi: 10.1523/JNEUROSCI.1071-09.2009. J Neurosci. 2009. PMID: 19605645 Free PMC article.

3

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM. Yang F, et al. Among authors: chen pp. J Biol Chem. 2005 Feb 18;280(7):5892-901. doi: 10.1074/jbc.M404751200. Epub 2004 Dec 7. J Biol Chem. 2005. PMID: 15590663 Free article.

4

Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.

Ma QL, Zuo X, Yang F, Ubeda OJ, Gant DJ, Alaverdyan M, Kiosea NC, Nazari S, Chen PP, Nothias F, Chan P, Teng E, Frautschy SA, Cole GM. Ma QL, et al. Among authors: chen pp. J Neurosci. 2014 May 21;34(21):7124-36. doi: 10.1523/JNEUROSCI.3439-13.2014. J Neurosci. 2014. PMID: 24849348 Free PMC article.

5

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals.

Hu S, Begum AN, Jones MR, Oh MS, Beech WK, Beech BH, Yang F, Chen P, Ubeda OJ, Kim PC, Davies P, Ma Q, Cole GM, Frautschy SA. Hu S, et al. Neurobiol Dis. 2009 Feb;33(2):193-206. doi: 10.1016/j.nbd.2008.10.007. Epub 2008 Nov 5. Neurobiol Dis. 2009. PMID: 19038340 Free PMC article.

6

Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization.

Teng E, Taylor K, Bilousova T, Weiland D, Pham T, Zuo X, Yang F, Chen PP, Glabe CG, Takacs A, Hoffman DR, Frautschy SA, Cole GM. Teng E, et al. Among authors: chen pp. Neurobiol Dis. 2015 Oct;82:552-560. doi: 10.1016/j.nbd.2015.09.002. Epub 2015 Sep 12. Neurobiol Dis. 2015. PMID: 26369878 Free PMC article.

7

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

Lim GP, Yang F, Chu T, Chen P, Beech W, Teter B, Tran T, Ubeda O, Ashe KH, Frautschy SA, Cole GM. Lim GP, et al. J Neurosci. 2000 Aug 1;20(15):5709-14. doi: 10.1523/JNEUROSCI.20-15-05709.2000. J Neurosci. 2000. PMID: 10908610 Free PMC article.

8

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

Teng E, Kepe V, Frautschy SA, Liu J, Satyamurthy N, Yang F, Chen PP, Cole GB, Jones MR, Huang SC, Flood DG, Trusko SP, Small GW, Cole GM, Barrio JR. Teng E, et al. Among authors: chen pp. Neurobiol Dis. 2011 Sep;43(3):565-75. doi: 10.1016/j.nbd.2011.05.003. Epub 2011 May 13. Neurobiol Dis. 2011. PMID: 21605674 Free PMC article.

9

Plaque-associated alpha-synuclein (NACP) pathology in aged transgenic mice expressing amyloid precursor protein.

Yang F, Uéda K, Chen P, Ashe KH, Cole GM. Yang F, et al. Brain Res. 2000 Jan 24;853(2):381-3. doi: 10.1016/s0006-8993(99)02207-6. Brain Res. 2000. PMID: 10640638

10

Boosting the durability of RuO₂ via confinement effect for proton exchange membrane water electrolyzer.

Zheng WX, Cheng XX, Chen PP, Wang LL, Duan Y, Feng GJ, Wang XR, Li JJ, Zhang C, Yu ZY, Lu TB. Zheng WX, et al. Among authors: chen pp. Nat Commun. 2025 Jan 2;16(1):337. doi: 10.1038/s41467-024-55747-0. Nat Commun. 2025. PMID: 39747082 Free PMC article.

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