Xu H - Search Results

1

Chromatin marks identify critical cell types for fine mapping complex trait variants.

Trynka G, Sandor C, Han B, Xu H, Stranger BE, Liu XS, Raychaudhuri S. Trynka G, et al. Among authors: xu h. Nat Genet. 2013 Feb;45(2):124-30. doi: 10.1038/ng.2504. Epub 2012 Dec 23. Nat Genet. 2013. PMID: 23263488 Free PMC article.

2

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification.

He HH, Meyer CA, Hu SS, Chen MW, Zang C, Liu Y, Rao PK, Fei T, Xu H, Long H, Liu XS, Brown M. He HH, et al. Among authors: xu h. Nat Methods. 2014 Jan;11(1):73-78. doi: 10.1038/nmeth.2762. Epub 2013 Dec 8. Nat Methods. 2014. PMID: 24317252 Free PMC article.

3

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.

Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium; Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium. Gusev A, et al. Among authors: xu h. Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6. Am J Hum Genet. 2014. PMID: 25439723 Free PMC article.

4

Sequence determinants of improved CRISPR sgRNA design.

Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Xu H, et al. Genome Res. 2015 Aug;25(8):1147-57. doi: 10.1101/gr.191452.115. Epub 2015 Jun 10. Genome Res. 2015. PMID: 26063738 Free PMC article.

5

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.

Trynka G, Westra HJ, Slowikowski K, Hu X, Xu H, Stranger BE, Klein RJ, Han B, Raychaudhuri S. Trynka G, et al. Among authors: xu h. Am J Hum Genet. 2015 Jul 2;97(1):139-52. doi: 10.1016/j.ajhg.2015.05.016. Am J Hum Genet. 2015. PMID: 26140449 Free PMC article.

6

Partitioning heritability by functional annotation using genome-wide association summary statistics.

Finucane HK, Bulik-Sullivan B, Gusev A, Trynka G, Reshef Y, Loh PR, Anttila V, Xu H, Zang C, Farh K, Ripke S, Day FR; ReproGen Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; RACI Consortium; Purcell S, Stahl E, Lindstrom S, Perry JR, Okada Y, Raychaudhuri S, Daly MJ, Patterson N, Neale BM, Price AL. Finucane HK, et al. Among authors: xu h. Nat Genet. 2015 Nov;47(11):1228-35. doi: 10.1038/ng.3404. Epub 2015 Sep 28. Nat Genet. 2015. PMID: 26414678 Free PMC article.

7

Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression.

Xu H, Xu K, He HH, Zang C, Chen CH, Chen Y, Qin Q, Wang S, Wang C, Hu S, Li F, Long H, Brown M, Liu XS. Xu H, et al. Among authors: xu k. Mol Cancer Res. 2016 Feb;14(2):163-172. doi: 10.1158/1541-7786.MCR-15-0313. Epub 2015 Dec 9. Mol Cancer Res. 2016. PMID: 26659825 Free PMC article.

8

Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.

Li W, Köster J, Xu H, Chen CH, Xiao T, Liu JS, Brown M, Liu XS. Li W, et al. Among authors: xu h. Genome Biol. 2015 Dec 16;16:281. doi: 10.1186/s13059-015-0843-6. Genome Biol. 2015. PMID: 26673418 Free PMC article.

9

CRISPR-DO for genome-wide CRISPR design and optimization.

Ma J, Köster J, Qin Q, Hu S, Li W, Chen C, Cao Q, Wang J, Mei S, Liu Q, Xu H, Liu XS. Ma J, et al. Among authors: xu h. Bioinformatics. 2016 Nov 1;32(21):3336-3338. doi: 10.1093/bioinformatics/btw476. Epub 2016 Jul 10. Bioinformatics. 2016. PMID: 27402906 Free PMC article.

10

ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline.

Qin Q, Mei S, Wu Q, Sun H, Li L, Taing L, Chen S, Li F, Liu T, Zang C, Xu H, Chen Y, Meyer CA, Zhang Y, Brown M, Long HW, Liu XS. Qin Q, et al. Among authors: xu h. BMC Bioinformatics. 2016 Oct 3;17(1):404. doi: 10.1186/s12859-016-1274-4. BMC Bioinformatics. 2016. PMID: 27716038 Free PMC article.

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