North TW - Search Results

1

Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages.

Gavegnano C, Detorio MA, Bassit L, Hurwitz SJ, North TW, Schinazi RF. Gavegnano C, et al. Among authors: north tw. Antimicrob Agents Chemother. 2013 Mar;57(3):1262-9. doi: 10.1128/AAC.02012-12. Epub 2012 Dec 21. Antimicrob Agents Chemother. 2013. PMID: 23263005 Free PMC article.

2

Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics.

North TW, Villalobos A, Hurwitz SJ, Deere JD, Higgins J, Chatterjee P, Tao S, Kauffman RC, Luciw PA, Kohler JJ, Schinazi RF. North TW, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3927-33. doi: 10.1128/AAC.02522-14. Epub 2014 Apr 28. Antimicrob Agents Chemother. 2014. PMID: 24777106 Free PMC article.

3

Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.

Hofman MJ, Higgins J, Matthews TB, Pedersen NC, Tan C, Schinazi RF, North TW. Hofman MJ, et al. Among authors: north tw. Antimicrob Agents Chemother. 2004 Sep;48(9):3483-90. doi: 10.1128/AAC.48.9.3483-3490.2004. Antimicrob Agents Chemother. 2004. PMID: 15328115 Free PMC article.

4

Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART.

Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW. Deere JD, et al. Among authors: north tw. PLoS One. 2014 Feb 5;9(2):e87914. doi: 10.1371/journal.pone.0087914. eCollection 2014. PLoS One. 2014. PMID: 24505331 Free PMC article.

5

Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW. Wadford DA, et al. Among authors: north tw. PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection 2014. PLoS One. 2014. PMID: 24498008 Free PMC article.

6

A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine.

Smith RA, Klarmann GJ, Stray KM, von Schwedler UK, Schinazi RF, Preston BD, North TW. Smith RA, et al. Among authors: north tw. Antimicrob Agents Chemother. 1999 Aug;43(8):2077-80. doi: 10.1128/AAC.43.8.2077. Antimicrob Agents Chemother. 1999. PMID: 10428942 Free PMC article.

7

Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.

North TW, Van Rompay KK, Higgins J, Matthews TB, Wadford DA, Pedersen NC, Schinazi RF. North TW, et al. J Virol. 2005 Jun;79(12):7349-54. doi: 10.1128/JVI.79.12.7349-7354.2005. J Virol. 2005. PMID: 15919889 Free PMC article.

8

Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS.

North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. North TW, et al. J Virol. 2010 Mar;84(6):2913-22. doi: 10.1128/JVI.02356-09. Epub 2009 Dec 23. J Virol. 2010. PMID: 20032180 Free PMC article.

9

Simian immunodeficiency virus macaque models of HIV latency.

Deere JD, Schinazi RF, North TW. Deere JD, et al. Among authors: north tw. Curr Opin HIV AIDS. 2011 Jan;6(1):57-61. doi: 10.1097/COH.0b013e32834086ce. Curr Opin HIV AIDS. 2011. PMID: 21242894 Free PMC article. Review.

10

Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.

Klarmann GJ, Smith RA, Schinazi RF, North TW, Preston BD. Klarmann GJ, et al. Among authors: north tw. J Biol Chem. 2000 Jan 7;275(1):359-66. doi: 10.1074/jbc.275.1.359. J Biol Chem. 2000. PMID: 10617626 Free article.

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