Renger JJ - Search Results

1

State-dependent properties of a new T-type calcium channel blocker enhance Ca(V)3.2 selectivity and support analgesic effects.

Francois A, Kerckhove N, Meleine M, Alloui A, Barrere C, Gelot A, Uebele VN, Renger JJ, Eschalier A, Ardid D, Bourinet E. Francois A, et al. Among authors: renger jj. Pain. 2013 Feb;154(2):283-293. doi: 10.1016/j.pain.2012.10.023. Epub 2012 Nov 5. Pain. 2013. PMID: 23257507

2

Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.

Uebele VN, Nuss CE, Fox SV, Garson SL, Cristescu R, Doran SM, Kraus RL, Santarelli VP, Li Y, Barrow JC, Yang ZQ, Schlegel KA, Rittle KE, Reger TS, Bednar RA, Lemaire W, Mullen FA, Ballard JE, Tang C, Dai G, McManus OB, Koblan KS, Renger JJ. Uebele VN, et al. Among authors: renger jj. Cell Biochem Biophys. 2009;55(2):81-93. doi: 10.1007/s12013-009-9057-4. Epub 2009 Jul 7. Cell Biochem Biophys. 2009. PMID: 19582593

3

Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of I(T)window.

Dreyfus FM, Tscherter A, Errington AC, Renger JJ, Shin HS, Uebele VN, Crunelli V, Lambert RC, Leresche N. Dreyfus FM, et al. Among authors: renger jj. J Neurosci. 2010 Jan 6;30(1):99-109. doi: 10.1523/JNEUROSCI.4305-09.2010. J Neurosci. 2010. PMID: 20053892 Free PMC article.

4

T-type calcium channel antagonism decreases motivation for nicotine and blocks nicotine- and cue-induced reinstatement for a response previously reinforced with nicotine.

Uslaner JM, Vardigan JD, Drott JM, Uebele VN, Renger JJ, Lee A, Li Z, Lê AD, Hutson PH. Uslaner JM, et al. Among authors: renger jj. Biol Psychiatry. 2010 Oct 15;68(8):712-8. doi: 10.1016/j.biopsych.2010.05.004. Epub 2010 Jul 1. Biol Psychiatry. 2010. PMID: 20579972

5

In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in mice.

Kraus RL, Li Y, Gregan Y, Gotter AL, Uebele VN, Fox SV, Doran SM, Barrow JC, Yang ZQ, Reger TS, Koblan KS, Renger JJ. Kraus RL, et al. Among authors: renger jj. J Pharmacol Exp Ther. 2010 Nov;335(2):409-17. doi: 10.1124/jpet.110.171058. Epub 2010 Aug 3. J Pharmacol Exp Ther. 2010. PMID: 20682849

6

Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2.

Cazade M, Nuss CE, Bidaud I, Renger JJ, Uebele VN, Lory P, Chemin J. Cazade M, et al. Among authors: renger jj. Mol Pharmacol. 2014 Feb;85(2):218-25. doi: 10.1124/mol.113.089581. Epub 2013 Nov 8. Mol Pharmacol. 2014. PMID: 24214826

7

Role of voltage-gated calcium channels in potassium-stimulated aldosterone secretion from rat adrenal zona glomerulosa cells.

Uebele VN, Nuss CE, Renger JJ, Connolly TM. Uebele VN, et al. Among authors: renger jj. J Steroid Biochem Mol Biol. 2004 Oct;92(3):209-18. doi: 10.1016/j.jsbmb.2004.04.012. J Steroid Biochem Mol Biol. 2004. PMID: 15555914

8

Minimal alterations in T-type calcium channel gating markedly modify physiological firing dynamics.

Tscherter A, David F, Ivanova T, Deleuze C, Renger JJ, Uebele VN, Shin HS, Bal T, Leresche N, Lambert RC. Tscherter A, et al. Among authors: renger jj. J Physiol. 2011 Apr 1;589(Pt 7):1707-24. doi: 10.1113/jphysiol.2010.203836. Epub 2011 Feb 14. J Physiol. 2011. PMID: 21320888 Free PMC article.

9

Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.

Yang ZQ, Barrow JC, Shipe WD, Schlegel KA, Shu Y, Yang FV, Lindsley CW, Rittle KE, Bock MG, Hartman GD, Uebele VN, Nuss CE, Fox SV, Kraus RL, Doran SM, Connolly TM, Tang C, Ballard JE, Kuo Y, Adarayan ED, Prueksaritanont T, Zrada MM, Marino MJ, Graufelds VK, DiLella AG, Reynolds IJ, Vargas HM, Bunting PB, Woltmann RF, Magee MM, Koblan KS, Renger JJ. Yang ZQ, et al. Among authors: renger jj. J Med Chem. 2008 Oct 23;51(20):6471-7. doi: 10.1021/jm800830n. Epub 2008 Sep 26. J Med Chem. 2008. PMID: 18817368

10

T-type calcium channels regulate cortical plasticity in-vivo. [corrected].

Uebele VN, Nuss CE, Santarelli VP, Garson SL, Kraus RL, Barrow JC, Stauffer SR, Koblan KS, Renger JJ, Aton S, Seibt J, Dumoulin M, Jha SK, Coleman T, Frank MG. Uebele VN, et al. Among authors: renger jj. Neuroreport. 2009 Feb 18;20(3):257-62. doi: 10.1097/WNR.0b013e3283200111. Neuroreport. 2009. PMID: 19212242 Free PMC article.

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