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Inferring statin-induced gene regulatory relationships in primary human hepatocytes.
Schröder A, Wollnik J, Wrzodek C, Dräger A, Bonin M, Burk O, Thomas M, Thasler WE, Zanger UM, Zell A. Schröder A, et al. Among authors: zell a. Bioinformatics. 2011 Sep 15;27(18):2473-7. doi: 10.1093/bioinformatics/btr416. Epub 2011 Jul 14. Bioinformatics. 2011. PMID: 21757465
The primary target of statins is HMG-CoA reductase, a key enzyme in cholesterol synthesis. However, statins elicit pleitropic responses including beneficial as well as adverse effects in the liver or other organs. ...AVAILABILITY: Microarray data are available at the Gene …
The primary target of statins is HMG-CoA reductase, a key enzyme in cholesterol synthesis. However, statins elicit pleitropic respons …
Qualitative translation of relations from BioPAX to SBML qual.
Büchel F, Wrzodek C, Mittag F, Dräger A, Eichner J, Rodriguez N, Le Novère N, Zell A. Büchel F, et al. Among authors: zell a. Bioinformatics. 2012 Oct 15;28(20):2648-53. doi: 10.1093/bioinformatics/bts508. Epub 2012 Aug 24. Bioinformatics. 2012. PMID: 22923304 Free PMC article.
Pathway-based visualization of cross-platform microarray datasets.
Wrzodek C, Eichner J, Zell A. Wrzodek C, et al. Among authors: zell a. Bioinformatics. 2012 Dec 1;28(23):3021-6. doi: 10.1093/bioinformatics/bts583. Epub 2012 Oct 9. Bioinformatics. 2012. PMID: 23047564
DNAm), in a pathway-centred manner. RESULTS: We present a novel pathway-based visualization method that is especially suitable for the visualization of high-throughput datasets from multiple different microarray platforms that were used for the analysis of diverse g …
DNAm), in a pathway-centred manner. RESULTS: We present a novel pathway-based visualization method that is especially suitable …
Integrated enrichment analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics data by using the InCroMAP software.
Eichner J, Rosenbaum L, Wrzodek C, Häring HU, Zell A, Lehmann R. Eichner J, et al. Among authors: zell a. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:77-82. doi: 10.1016/j.jchromb.2014.04.030. Epub 2014 Apr 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24811976
JSBML: a flexible Java library for working with SBML.
Dräger A, Rodriguez N, Dumousseau M, Dörr A, Wrzodek C, Le Novère N, Zell A, Hucka M. Dräger A, et al. Among authors: zell a. Bioinformatics. 2011 Aug 1;27(15):2167-8. doi: 10.1093/bioinformatics/btr361. Epub 2011 Jun 22. Bioinformatics. 2011. PMID: 21697129 Free PMC article.
112 results