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Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons.
Escobar-Khondiker M, Höllerhage M, Muriel MP, Champy P, Bach A, Depienne C, Respondek G, Yamada ES, Lannuzel A, Yagi T, Hirsch EC, Oertel WH, Jacob R, Michel PP, Ruberg M, Höglinger GU. Escobar-Khondiker M, et al. Among authors: respondek g. J Neurosci. 2007 Jul 18;27(29):7827-37. doi: 10.1523/JNEUROSCI.1644-07.2007. J Neurosci. 2007. PMID: 17634376 Free PMC article.
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
Höglinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang LS, Klei L, Rademakers R, de Silva R, Litvan I, Riley DE, van Swieten JC, Heutink P, Wszolek ZK, Uitti RJ, Vandrovcova J, Hurtig HI, Gross RG, Maetzler W, Goldwurm S, Tolosa E, Borroni B, Pastor P; PSP Genetics Study Group; Cantwell LB, Han MR, Dillman A, van der Brug MP, Gibbs JR, Cookson MR, Hernandez DG, Singleton AB, Farrer MJ, Yu CE, Golbe LI, Revesz T, Hardy J, Lees AJ, Devlin B, Hakonarson H, Müller U, Schellenberg GD. Höglinger GU, et al. Nat Genet. 2011 Jun 19;43(7):699-705. doi: 10.1038/ng.859. Nat Genet. 2011. PMID: 21685912 Free PMC article.
Accuracy of the National Institute for Neurological Disorders and Stroke/Society for Progressive Supranuclear Palsy and neuroprotection and natural history in Parkinson plus syndromes criteria for the diagnosis of progressive supranuclear palsy.
Respondek G, Roeber S, Kretzschmar H, Troakes C, Al-Sarraj S, Gelpi E, Gaig C, Chiu WZ, van Swieten JC, Oertel WH, Höglinger GU. Respondek G, et al. Mov Disord. 2013 Apr;28(4):504-9. doi: 10.1002/mds.25327. Epub 2013 Feb 21. Mov Disord. 2013. PMID: 23436751
Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice.
Yamada ES, Respondek G, Müssner S, de Andrade A, Höllerhage M, Depienne C, Rastetter A, Tarze A, Friguet B, Salama M, Champy P, Oertel WH, Höglinger GU. Yamada ES, et al. Among authors: respondek g. Exp Neurol. 2014 Mar;253:113-25. doi: 10.1016/j.expneurol.2013.12.017. Epub 2014 Jan 3. Exp Neurol. 2014. PMID: 24389273 Free article.
The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases.
Respondek G, Stamelou M, Kurz C, Ferguson LW, Rajput A, Chiu WZ, van Swieten JC, Troakes C, Al Sarraj S, Gelpi E, Gaig C, Tolosa E, Oertel WH, Giese A, Roeber S, Arzberger T, Wagenpfeil S, Höglinger GU; Movement Disorder Society-endorsed PSP Study Group. Respondek G, et al. Mov Disord. 2014 Dec;29(14):1758-66. doi: 10.1002/mds.26054. Epub 2014 Nov 5. Mov Disord. 2014. PMID: 25370486
Piericidin A aggravates Tau pathology in P301S transgenic mice.
Höllerhage M, Deck R, De Andrade A, Respondek G, Xu H, Rösler TW, Salama M, Carlsson T, Yamada ES, Gad El Hak SA, Goedert M, Oertel WH, Höglinger GU. Höllerhage M, et al. Among authors: respondek g. PLoS One. 2014 Dec 1;9(12):e113557. doi: 10.1371/journal.pone.0113557. eCollection 2014. PLoS One. 2014. PMID: 25437199 Free PMC article.
72 results