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Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes.
Furukawa S, Haruta M, Arai Y, Honda S, Ohshima J, Sugawara W, Kageyama Y, Higashi Y, Nishida K, Tsunematsu Y, Nakadate H, Ishii M, Kaneko Y. Furukawa S, et al. Among authors: arai y. Cancer Sci. 2009 Apr;100(4):698-708. doi: 10.1111/j.1349-7006.2009.01102.x. Epub 2009 Feb 24. Cancer Sci. 2009. PMID: 19245437 Free PMC article.
Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed in patients with Li-Fraumeni or Li-Fraumeni-like syndrome.
Sugawara W, Arai Y, Kasai F, Fujiwara Y, Haruta M, Hosaka R, Nishida K, Kurosumi M, Kobayashi Y, Akagi K, Kaneko Y. Sugawara W, et al. Among authors: arai y. Genes Chromosomes Cancer. 2011 Jul;50(7):535-45. doi: 10.1002/gcc.20878. Epub 2011 Apr 11. Genes Chromosomes Cancer. 2011. PMID: 21484931
4,210 results