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Pathogenic C difficile is here (and everywhere) to stay.
Warren CA, Guerrant RL. Warren CA, et al. Among authors: guerrant rl. Lancet. 2011 Jan 1;377(9759):8-9. doi: 10.1016/S0140-6736(10)61885-5. Lancet. 2011. PMID: 21084110 No abstract available.
Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model.
Warren CA, van Opstal E, Ballard TE, Kennedy A, Wang X, Riggins M, Olekhnovich I, Warthan M, Kolling GL, Guerrant RL, Macdonald TL, Hoffman PS. Warren CA, et al. Among authors: guerrant rl. Antimicrob Agents Chemother. 2012 Aug;56(8):4103-11. doi: 10.1128/AAC.00360-12. Epub 2012 May 14. Antimicrob Agents Chemother. 2012. PMID: 22585229 Free PMC article.
Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice.
Warren CA, van Opstal EJ, Riggins MS, Li Y, Moore JH, Kolling GL, Guerrant RL, Hoffman PS. Warren CA, et al. Among authors: guerrant rl. Antimicrob Agents Chemother. 2013 Feb;57(2):689-96. doi: 10.1128/AAC.00877-12. Epub 2012 Nov 12. Antimicrob Agents Chemother. 2013. PMID: 23147742 Free PMC article.
Intestinal epithelial restitution after TcdB challenge and recovery from Clostridium difficile infection in mice with alanyl-glutamine treatment.
Rodrigues RS, Oliveira RA, Li Y, Zaja-Milatovic S, Costa LB, Braga Neto MB, Kolling GL, Lima AA, Guerrant RL, Warren CA. Rodrigues RS, et al. Among authors: guerrant rl. J Infect Dis. 2013 May 15;207(10):1505-15. doi: 10.1093/infdis/jit041. Epub 2013 Jan 28. J Infect Dis. 2013. PMID: 23359592 Free PMC article.
Treatment of Clostridium difficile infection using SQ641, a capuramycin analogue, increases post-treatment survival and improves clinical measures of disease in a murine model.
Moore JH 2nd, van Opstal E, Kolling GL, Shin JH, Bogatcheva E, Nikonenko B, Einck L, Phipps AJ, Guerrant RL, Protopopova M, Warren CA. Moore JH 2nd, et al. Among authors: guerrant rl. J Antimicrob Chemother. 2016 May;71(5):1300-6. doi: 10.1093/jac/dkv479. Epub 2016 Jan 31. J Antimicrob Chemother. 2016. PMID: 26832756 Free PMC article.
490 results