Debien L - Search Results

1

Three-carbon homologation of diorganozincs with lithiated acetylenic epoxides.

Denichoux A, Debien L, Cyklinsky M, Kaci M, Chemla F, Ferreira F, Pérez-Luna A. Denichoux A, et al. Among authors: debien l. J Org Chem. 2013 Jan 4;78(1):134-45. doi: 10.1021/jo302128n. Epub 2012 Dec 17. J Org Chem. 2013. PMID: 23210857

2

A two-step synthesis of α-keto vinyl carbinols from ketones.

Debien L, Zard SZ. Debien L, et al. Org Lett. 2013 Dec 6;15(23):6066-9. doi: 10.1021/ol4029594. Epub 2013 Nov 11. Org Lett. 2013. PMID: 24215234

3

Modular approach to saturated and α,β-unsaturated ketones.

Debien L, Quiclet-Sire B, Zard SZ. Debien L, et al. Org Lett. 2011 Oct 21;13(20):5676-9. doi: 10.1021/ol202399c. Epub 2011 Sep 28. Org Lett. 2011. PMID: 21954958

4

A convergent, unified approach to functionalized fluoro- and trifluoromethyl alkenes.

Debien L, Quiclet-Sire B, Zard SS. Debien L, et al. Org Lett. 2012 Oct 5;14(19):5118-21. doi: 10.1021/ol3023903. Epub 2012 Sep 24. Org Lett. 2012. PMID: 23005034

5

Tri- and tetrasubstituted functionalized vinyl sulfides by radical allylation.

Debien L, Braun MG, Quiclet-Sire B, Zard SZ. Debien L, et al. Org Lett. 2013 Dec 20;15(24):6250-3. doi: 10.1021/ol403103u. Epub 2013 Nov 23. Org Lett. 2013. PMID: 24266882

6

From a remarkable manifestation of polar effects in a radical fragmentation to the convergent synthesis of highly functionalized ketones.

Debien L, Zard SZ. Debien L, et al. J Am Chem Soc. 2013 Mar 13;135(10):3808-11. doi: 10.1021/ja400831w. Epub 2013 Feb 26. J Am Chem Soc. 2013. PMID: 23425262

7

Allylic alcohols: ideal radical allylating agents?

Debien L, Quiclet-Sire B, Zard SZ. Debien L, et al. Acc Chem Res. 2015 May 19;48(5):1237-53. doi: 10.1021/acs.accounts.5b00019. Epub 2015 Apr 23. Acc Chem Res. 2015. PMID: 25905563

8

Palladium-Catalyzed Trimethylenemethane Cycloaddition of Olefins Activated by the σ-Electron-Withdrawing Trifluoromethyl Group.

Trost BM, Debien L. Trost BM, et al. Among authors: debien l. J Am Chem Soc. 2015 Sep 16;137(36):11606-9. doi: 10.1021/jacs.5b07573. Epub 2015 Sep 8. J Am Chem Soc. 2015. PMID: 26291872

9

Re-Orienting Coupling of Organocuprates with Propargyl Electrophiles from S_N2' to S_N2 with Stereocontrol.

Trost BM, Debien L. Trost BM, et al. Among authors: debien l. Chem Sci. 2016;7(8):4985-4989. doi: 10.1039/C6SC01086E. Epub 2016 May 10. Chem Sci. 2016. PMID: 28066535 Free PMC article.

10

Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73.

Beatty JW, Lindsey EA, Thomas-Tran R, Debien L, Mandal D, Jeffrey JL, Tran AT, Fournier J, Jacob SD, Yan X, Drew SL, Ginn E, Chen A, Pham AT, Zhao S, Jin L, Young SW, Walker NP, Leleti MR, Moschütz S, Sträter N, Powers JP, Lawson KV. Beatty JW, et al. Among authors: debien l. J Med Chem. 2020 Apr 23;63(8):3935-3955. doi: 10.1021/acs.jmedchem.9b01713. Epub 2020 Apr 8. J Med Chem. 2020. PMID: 32212732

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