Chen D - Search Results

1

Functional characterization of Klippel-Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation and angiogenesis during embryogenesis.

Chen D, Li L, Tu X, Yin Z, Wang Q. Chen D, et al. Hum Mol Genet. 2013 Mar 1;22(5):963-76. doi: 10.1093/hmg/dds501. Epub 2012 Nov 29. Hum Mol Genet. 2013. PMID: 23197652

2

Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish.

Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK. Li L, et al. Among authors: chen d. Blood. 2014 Jan 23;123(4):501-8. doi: 10.1182/blood-2013-07-514612. Epub 2013 Nov 25. Blood. 2014. PMID: 24277077 Free PMC article.

3

PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation.

Zhang M, Xie R, Hou W, Wang B, Shen R, Wang X, Wang Q, Zhu T, Jonason JH, Chen D. Zhang M, et al. Among authors: chen d. J Cell Sci. 2009 May 1;122(Pt 9):1382-9. doi: 10.1242/jcs.040709. Epub 2009 Apr 7. J Cell Sci. 2009. PMID: 19351720 Free PMC article.

4

Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2.

Wang Q, Wei X, Zhu T, Zhang M, Shen R, Xing L, O'Keefe RJ, Chen D. Wang Q, et al. Among authors: chen d. J Biol Chem. 2007 Apr 6;282(14):10742-8. doi: 10.1074/jbc.M610997200. Epub 2007 Jan 10. J Biol Chem. 2007. PMID: 17215250 Free PMC article.

5

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.

Su N, Sun Q, Li C, Lu X, Qi H, Chen S, Yang J, Du X, Zhao L, He Q, Jin M, Shen Y, Chen D, Chen L. Su N, et al. Among authors: chen l, chen s, chen d. Hum Mol Genet. 2010 Apr 1;19(7):1199-210. doi: 10.1093/hmg/ddp590. Epub 2010 Jan 6. Hum Mol Genet. 2010. PMID: 20053668 Free PMC article.

6

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

Jin M, Yu Y, Qi H, Xie Y, Su N, Wang X, Tan Q, Luo F, Zhu Y, Wang Q, Du X, Xian CJ, Liu P, Huang H, Shen Y, Deng CX, Chen D, Chen L. Jin M, et al. Among authors: chen l, chen d. Hum Mol Genet. 2012 Dec 15;21(26):5443-55. doi: 10.1093/hmg/dds390. Epub 2012 Sep 26. Hum Mol Genet. 2012. PMID: 23014564 Free PMC article.

7

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling.

Sun X, Zhang R, Chen H, Du X, Chen S, Huang J, Liu M, Xu M, Luo F, Jin M, Su N, Qi H, Yang J, Tan Q, Zhang D, Ni Z, Liang S, Zhang B, Chen D, Zhang X, Luo L, Chen L, Xie Y. Sun X, et al. Among authors: chen l, chen s, chen d, chen h. Theranostics. 2020 May 30;10(16):7111-7130. doi: 10.7150/thno.45286. eCollection 2020. Theranostics. 2020. PMID: 32641982 Free PMC article.

8

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.

Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L. Sun X, et al. Among authors: chen l, chen b, chen s, chen d, chen h. Nat Commun. 2020 Jan 24;11(1):479. doi: 10.1038/s41467-019-14169-z. Nat Commun. 2020. PMID: 31980602 Free PMC article.

9

ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.

Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G. Zhu K, et al. Among authors: chen d. J Bone Miner Res. 2013 Sep;28(9):1870-1884. doi: 10.1002/jbmr.1958. J Bone Miner Res. 2013. PMID: 23649506 Free PMC article.

10

Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.

Cao H, Zhu K, Qiu L, Li S, Niu H, Hao M, Yang S, Zhao Z, Lai Y, Anderson JL, Fan J, Im HJ, Chen D, Roodman GD, Xiao G. Cao H, et al. Among authors: chen d. J Biol Chem. 2013 Oct 18;288(42):30399-30410. doi: 10.1074/jbc.M113.469973. Epub 2013 Sep 4. J Biol Chem. 2013. PMID: 24005670 Free PMC article. Clinical Trial.

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