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Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death.
Rubini-Dias L, Fernandes TVA, de Souza MP, Hottz D, Arruda AT, Borges AA, Ouverney G, da Silva FC, Forezi LDSM, Limaverde-Sousa G, Robbs BK. Rubini-Dias L, et al. Among authors: arruda at. Biomedicines. 2024 Dec 21;12(12):2916. doi: 10.3390/biomedicines12122916. Biomedicines. 2024. PMID: 39767822 Free PMC article.
An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup.
Gower M, Li X, Aguilar-Navarro AG, Lin B, Fernandez M, Edun G, Nader M, Rondeau V, Arruda A, Tierens A, Eames Seffernick A, Pölönen P, Durocher J, Wagenblast E, Yang L, Lee HS, Mullighan CG, Teachey D, Rashkovan M, Tremblay CS, Herranz D, Itkin T, Loghavi S, Dick JE, Schwartz G, Perusini MA, Sibai H, Hitzler J, Gruber TA, Minden M, Jones CL, Dolgalev I, Jahangiri S, Tikhonova AN. Gower M, et al. Among authors: arruda a. Sci Transl Med. 2025 Jan;17(779):eadr2012. doi: 10.1126/scitranslmed.adr2012. Epub 2025 Jan 1. Sci Transl Med. 2025. PMID: 39742502
2024 Update of the RECOVER-Adult Long COVID Research Index.
Geng LN, Erlandson KM, Hornig M, Letts R, Selvaggi C, Ashktorab H, Atieh O, Bartram L, Brim H, Brosnahan SB, Brown J, Castro M, Charney A, Chen P, Deeks SG, Erdmann N, Flaherman VJ, Ghamloush MA, Goepfert P, Goldman JD, Han JE, Hess R, Hirshberg E, Hoover SE, Katz SD, Kelly JD, Klein JD, Krishnan JA, Lee-Iannotti J, Levitan EB, Marconi VC, Metz TD, Modes ME, Nikolich JŽ, Novak RM, Ofotokun I, Okumura MJ, Parthasarathy S, Patterson TF, Peluso MJ, Poppas A, Quintero Cardona O, Scott J, Shellito J, Sherif ZA, Singer NG, Taylor BS, Thaweethai T, Verduzco-Gutierrez M, Wisnivesky J, McComsey GA, Horwitz LI, Foulkes AS; RECOVER Consortium. Geng LN, et al. JAMA. 2024 Dec 18. doi: 10.1001/jama.2024.24184. Online ahead of print. JAMA. 2024. PMID: 39693079
Using diagnostic data from veterinary diagnostic laboratories to unravel macroepidemiological aspects of porcine circoviruses 2 and 3 in the United States from 2002-2023.
Cezar G, Magalhães E, Rupasinghe K, Chandra S, Silva G, Almeida M, Crim B, Burrough E, Gauger P, Siepker C, Mainenti M, Zeller M, Fano E, Piñeyro P, Main R, Thurn M, Lages P, Corzo C, Rovira A, Naikare H, McGaughey R, Matias-Ferreyra F, Retallick J, Gebhardt J, Greseth J, Kersey D, Clement T, Pillatzki A, Christopher-Hennings J, Prarat M, Johnson A, Summers D, Bowen C, Boyle J, Hendrix K, Arruda AG, Linhares D, Trevisan G. Cezar G, et al. Among authors: arruda ag. PLoS One. 2024 Dec 10;19(12):e0311807. doi: 10.1371/journal.pone.0311807. eCollection 2024. PLoS One. 2024. PMID: 39656698 Free PMC article.
Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses.
Bocher O, Singh A, Huang Y, Võsa U, Reimann E, Arruda A, Barysenska A, Kolde A, Rayner NW; Estonian Biobank research team; Esko T, Mägi R, Zeggini E. Bocher O, et al. Among authors: arruda a. PLoS Genet. 2024 Dec 3;20(12):e1011346. doi: 10.1371/journal.pgen.1011346. eCollection 2024 Dec. PLoS Genet. 2024. PMID: 39625957 Free PMC article.
Acute myeloid leukemia drug tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing.
Morgenstern Y, Lee J, Na Y, Lieng BY, Ly NS, Gwynne WD, Hurren R, Ma L, Ling D, Gronda M, Arruda A, Frisch A, Zuckerman T, Ofran Y, Minden MD, Zhang L, O'Brien C, Quaile AT, Montenegro-Burke JR, Schimmer AD. Morgenstern Y, et al. Among authors: arruda a. Haematologica. 2024 Nov 21. doi: 10.3324/haematol.2024.286018. Online ahead of print. Haematologica. 2024. PMID: 39568440 Free article.
394 results