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MoA Studies of the TEAD P-Site Binding Ligand MSC-4106 and Its Optimization to TEAD1-Selective Amide M3686.
Heinrich T, Schwarz D, Petersson C, Gunera J, Garg S, Schneider R, Keil M, Grimmeisen L, Unzue Lopez A, Albers L, Schlesiger S, Gambardella A, Bomke J, Carswell E, Schilke H, Diehl P, Doerfel B, Musil D, Trivier E, Broome R, Marshall S, Balsiger A, Friedrich E, Lemos AR, Santos SP, Sousa PMF, Freire F, Bandeiras TM, Bortoluzzi A, Wienke D. Heinrich T, et al. Among authors: schneider r. J Med Chem. 2024 Dec 20. doi: 10.1021/acs.jmedchem.4c01949. Online ahead of print. J Med Chem. 2024. PMID: 39704449
A dormant overmassive black hole in the early Universe.
Juodžbalis I, Maiolino R, Baker WM, Tacchella S, Scholtz J, D'Eugenio F, Witstok J, Schneider R, Trinca A, Valiante R, DeCoursey C, Curti M, Carniani S, Chevallard J, de Graaff A, Arribas S, Bennett JS, Bourne MA, Bunker AJ, Charlot S, Jiang B, Koudmani S, Perna M, Robertson B, Sijacki D, Übler H, Williams CC, Willott C. Juodžbalis I, et al. Among authors: schneider r. Nature. 2024 Dec;636(8043):594-597. doi: 10.1038/s41586-024-08210-5. Epub 2024 Dec 18. Nature. 2024. PMID: 39695212 Free PMC article.
Improvement of Transmural Inflammation With Adalimumab Versus Immunomodulator Maintenance Therapy in Pediatric Crohn's Disease: Single-Center Prospective Evaluation Using the Pediatric Inflammatory Crohn's Magnetic Resonance Enterography Index.
Scarallo L, McKay HE, Schneider R, Ricciuto A, Walters TD, Greer MC, Griffiths AM, Church PC. Scarallo L, et al. Among authors: schneider r. Inflamm Bowel Dis. 2024 Dec 17:izae227. doi: 10.1093/ibd/izae227. Online ahead of print. Inflamm Bowel Dis. 2024. PMID: 39688854
Response from the Canadian Children Inflammatory Bowel Disease Network to the US Food and Drug Administration Draft Guidance for Industry on pediatric inflammatory bowel disease: developing drugs for treatment.
Wine E, deBruyn J, Crowley E, Griffiths AM; Canadian Children IBD Network. Wine E, et al. J Can Assoc Gastroenterol. 2024 Oct 12;7(6):397-398. doi: 10.1093/jcag/gwae034. eCollection 2024 Dec. J Can Assoc Gastroenterol. 2024. PMID: 39679099 Free PMC article. No abstract available.
Using interactive platforms to encode, manage and explore immune-related adverse outcome pathways.
Mazein A, Shoaib M, Alb M, Sakellariou C, Sommer C, Sewald K, Reiche K, Gogesch P, Roser LA, Ortega Iannazzo S, Sheth S, Schiffmann S, Waibler Z, Neuhaus V, Dehmel S, Satagopam V, Schneider R, Ostaszewski M, Gu W. Mazein A, et al. Among authors: schneider r. J Immunotoxicol. 2024 Oct;21(sup1):S5-S12. doi: 10.1080/1547691X.2024.2345154. Epub 2024 Dec 10. J Immunotoxicol. 2024. PMID: 39655493 Free article.
3,974 results