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Page 1
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H. Kleinschnitz C, et al. Among authors: schuhmann mk. Blood. 2013 Jan 24;121(4):679-91. doi: 10.1182/blood-2012-04-426734. Epub 2012 Nov 15. Blood. 2013. PMID: 23160472 Free PMC article.
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E, Mittal M, Barit D, Schwarz T, Geis C, Kraft P, Barthel K, Schuhmann MK, Herrmann AM, Meuth SG, Stoll G, Meurer S, Schrewe A, Becker L, Gailus-Durner V, Fuchs H, Klopstock T, de Angelis MH, Jandeleit-Dahm K, Shah AM, Weissmann N, Schmidt HH. Kleinschnitz C, et al. Among authors: schuhmann mk. PLoS Biol. 2010 Sep 21;8(9):e1000479. doi: 10.1371/journal.pbio.1000479. PLoS Biol. 2010. PMID: 20877715 Free PMC article.
Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death.
Herrmann AM, Göbel K, Simon OJ, Melzer N, Schuhmann MK, Stenner MP, Weishaupt A, Kleinschnitz C, Bittner S, Meuth P, Stuve O, Budde T, Kieseier BC, Wiendl H, Meuth SG. Herrmann AM, et al. Among authors: schuhmann mk. Am J Pathol. 2010 Dec;177(6):3051-60. doi: 10.2353/ajpath.2010.100442. Epub 2010 Oct 29. Am J Pathol. 2010. PMID: 21037084 Free PMC article.
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level.
Göbel K, Bittner S, Melzer N, Pankratz S, Dreykluft A, Schuhmann MK, Meuth SG, Wiendl H. Göbel K, et al. Among authors: schuhmann mk. J Neuroinflammation. 2012 Feb 28;9:41. doi: 10.1186/1742-2094-9-41. J Neuroinflammation. 2012. PMID: 22373353 Free PMC article.
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.
Bittner S, Ruck T, Schuhmann MK, Herrmann AM, Moha ou Maati H, Bobak N, Göbel K, Langhauser F, Stegner D, Ehling P, Borsotto M, Pape HC, Nieswandt B, Kleinschnitz C, Heurteaux C, Galla HJ, Budde T, Wiendl H, Meuth SG. Bittner S, et al. Among authors: schuhmann mk. Nat Med. 2013 Sep;19(9):1161-5. doi: 10.1038/nm.3303. Epub 2013 Aug 11. Nat Med. 2013. PMID: 23933981
Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis.
Lanz TV, Becker S, Osswald M, Bittner S, Schuhmann MK, Opitz CA, Gaikwad S, Wiestler B, Litzenburger UM, Sahm F, Ott M, Iwantscheff S, Grabitz C, Mittelbronn M, von Deimling A, Winkler F, Meuth SG, Wick W, Platten M. Lanz TV, et al. Among authors: schuhmann mk. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14735-40. doi: 10.1073/pnas.1302569110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959874 Free PMC article.
100 results