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Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia.
Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, Kleinman JE, Weinberger DR. Egan MF, et al. Among authors: straub re. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12604-9. doi: 10.1073/pnas.0405077101. Epub 2004 Aug 13. Proc Natl Acad Sci U S A. 2004. PMID: 15310849 Free PMC article.
GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss.
Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, Straub RE. Addington AM, et al. Among authors: straub re. Mol Psychiatry. 2005 Jun;10(6):581-8. doi: 10.1038/sj.mp.4001599. Mol Psychiatry. 2005. PMID: 15505639 Clinical Trial.
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia.
Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, Goldberg TE, Weinberger DR. Callicott JH, et al. Among authors: straub re. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8627-32. doi: 10.1073/pnas.0500515102. Epub 2005 Jun 6. Proc Natl Acad Sci U S A. 2005. PMID: 15939883 Free PMC article.
174 results