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In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept.
Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. Ioannou Y, et al. Among authors: pericleous c. J Thromb Haemost. 2009 May;7(5):833-42. doi: 10.1111/j.1538-7836.2009.03316.x. Epub 2009 Feb 12. J Thromb Haemost. 2009. PMID: 19220729 Free article.
Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions.
Giles I, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S, Rahman A. Giles I, et al. Among authors: pericleous c. J Immunol. 2009 Apr 15;182(8):4836-43. doi: 10.4049/jimmunol.0804241. J Immunol. 2009. PMID: 19342662 Free article.
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways.
Lambrianides A, Carroll CJ, Pierangeli SS, Pericleous C, Branch W, Rice J, Latchman DS, Townsend P, Isenberg DA, Rahman A, Giles IP. Lambrianides A, et al. Among authors: pericleous c. J Immunol. 2010 Jun 15;184(12):6622-8. doi: 10.4049/jimmunol.0902765. Epub 2010 May 17. J Immunol. 2010. PMID: 20483743 Free PMC article.
New therapeutic targets for the antiphospholipid syndrome.
Pericleous C, Ioannou Y. Pericleous C, et al. Expert Opin Ther Targets. 2010 Dec;14(12):1291-9. doi: 10.1517/14728222.2010.524207. Epub 2010 Sep 28. Expert Opin Ther Targets. 2010. PMID: 20874375 Review.
53 results