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Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S; CHARTER Group. Croteau D, et al. Among authors: marra cm. J Antimicrob Chemother. 2013 Mar;68(3):684-9. doi: 10.1093/jac/dks441. Epub 2012 Nov 9. J Antimicrob Chemother. 2013. PMID: 23143899 Free PMC article.
HIV-associated dementia.
Major EO, Rausch D, Marra C, Clifford D. Major EO, et al. Science. 2000 Apr 21;288(5465):440-2. doi: 10.1126/science.288.5465.439d. Science. 2000. PMID: 10798979 No abstract available.
A randomized clinical trial of CPI-1189 for HIV-associated cognitive-motor impairment.
Clifford DB, McArthur JC, Schifitto G, Kieburtz K, McDermott MP, Letendre S, Cohen BA, Marder K, Ellis RJ, Marra CM; Neurologic AIDS Research Consortium. Clifford DB, et al. Among authors: marra cm. Neurology. 2002 Nov 26;59(10):1568-73. doi: 10.1212/01.wnl.0000034177.47015.da. Neurology. 2002. PMID: 12451199 Clinical Trial.
HIV neuropathy natural history cohort study: assessment measures and risk factors.
Simpson DM, Kitch D, Evans SR, McArthur JC, Asmuth DM, Cohen B, Goodkin K, Gerschenson M, So Y, Marra CM, Diaz-Arrastia R, Shriver S, Millar L, Clifford DB; ACTG A5117 Study Group. Simpson DM, et al. Among authors: marra cm. Neurology. 2006 Jun 13;66(11):1679-87. doi: 10.1212/01.wnl.0000218303.48113.5d. Neurology. 2006. PMID: 16769940 Clinical Trial.
194 results